Ryan R, Tilton R C
Antimicrob Agents Chemother. 1977 Jan;11(1):114-7. doi: 10.1128/AAC.11.1.114.
A rapid method for determining the minimal inhibition concentrations (MICs) of ampicillin using Haemophilus influenzae as the test organism is described. This semiautomated technique using the Autobac system was compared with the agar dilution MIC method. Fifty-seven isolates of both susceptible and resistant H. influenzae were tested. There was exact quantitative agreement with 65% of the isolates, and 91% of the isolates showed no more than a one-dilution-interval difference when MICs were determined by both methods. Total testing time was 3 to 4 h.
描述了一种使用流感嗜血杆菌作为测试生物体来测定氨苄青霉素最小抑菌浓度(MIC)的快速方法。将这种使用自动细菌鉴定系统的半自动技术与琼脂稀释MIC方法进行了比较。对57株敏感和耐药的流感嗜血杆菌分离株进行了测试。两种方法测定的MIC值对65%的分离株完全一致,91%的分离株两种方法测定的MIC值差异不超过一个稀释度间隔。总测试时间为3至4小时。