Adverse reactions such as vomiting, excessive intestinal gas and falling asleep at the breast have been reported in breastfed infants whose mothers were taking oral chloramphenicol. Milk concentrations are not sufficient to induce "gray baby" syndrome, but since chloramphenicol-induced aplastic anemia is not dose-related, this might occur, but has not been reported. An alternate drug is preferred to chloramphenicol during breastfeeding, especially while nursing a newborn or preterm infant. If the mother must receive chloramphenicol during nursing, monitor the infant for gastrointestinal disturbances and adequacy of nursing. Monitoring of the infant's complete blood count and differential is advisable. In some cases, discontinuation of breastfeeding might be preferred.
据报道，母亲服用口服氯霉素时，母乳喂养的婴儿会出现诸如呕吐、肠道气体过多和在吃奶时入睡等不良反应。乳汁中的氯霉素浓度不足以诱发“灰婴综合征”，但由于氯霉素所致的再生障碍性贫血与剂量无关，这种情况可能会发生，但尚未见报道。母乳喂养期间，尤其是喂养新生儿或早产儿期间，首选替代药物而非氯霉素。如果母亲在哺乳期间必须接受氯霉素治疗，需监测婴儿有无胃肠道不适以及哺乳是否充足。建议监测婴儿的全血细胞计数及分类。在某些情况下，可能更倾向于停止母乳喂养。
