Graduate Program in Physical Education, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.
Department of Nutrition, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.
Nutrients. 2018 Jul 12;10(7):889. doi: 10.3390/nu10070889.
This study investigated the effect of high-intensity interval (HIIE) and moderate-intensity continuous exercise (MICE) on glucagon-like peptide 1 (GLP-1), appetite and energy intake (EI) in obese men. In a randomized crossover trial, 12 participants (28.4 ± 2.6 years, 35.5 ± 4.5 kg/m², 39.8 ± 2.2% body fat) performed: (I) Control (CON, no exercise); (II) MICE (20 min, 70% of maximal heart rate) and (III) HIIE (10 × 1 min at 90% of maximal heart rate with 1 min recovery). GLP-1 and appetite were assessed at: (I) PRE: pre-exercise; (II) POST: immediately post-exercise; (III) POST-1 h: 1 h post-exercise. EI was assessed after an meal offered 1 h post-exercise and over 24 h. There was a significant time × condition interaction for GLP-1 ( = 0.035). Higher GLP-1 levels in MICE vs. CON ( = 0.024) and a trend for HIIE vs. CON ( = 0.069) POST-1h was found. Hunger was reduced immediately post-HIIE compared to CON ( < 0.01), but was not sustained POST-1 h ( > 0.05). EI did not differ between the sessions 1 h post-exercise or over 24H ( > 0.05). In summary, although MICE increased GLP-1 levels POST-1h and HIIE induced a transient reduction in hunger, both exercise protocols did not impact EI in obese men.
这项研究调查了高强度间歇训练（HIIE）和中等强度持续运动（MICE）对肥胖男性胰高血糖素样肽 1（GLP-1）、食欲和能量摄入（EI）的影响。在一项随机交叉试验中，12 名参与者（28.4 ± 2.6 岁，35.5 ± 4.5kg/m²，39.8 ± 2.2%体脂）进行了以下三种运动：（I）对照（CON，不运动）；（II）MICE（20 分钟，最大心率的 70%）和（III）HIIE（10×1 分钟，最大心率的 90%，恢复 1 分钟）。GLP-1 和食欲在以下时间点进行评估：（I）PRE：运动前；（II）POST：运动后即刻；（III）POST-1 h：运动后 1 小时。EI 在运动后 1 小时提供的一顿饭后和 24 小时内进行评估。GLP-1 存在显著的时间×条件交互作用（ = 0.035）。与 CON 相比，MICE 组的 GLP-1 水平更高（ = 0.024），HIIE 组也有趋势（ = 0.069）。与 CON 相比，HIIE 后即刻饥饿感降低（ < 0.01），但 1 小时后（ > 0.05）饥饿感并未持续降低。运动后 1 小时或 24 小时内的 EI 无差异（ > 0.05）。总之，尽管 MICE 增加了 POST-1 h 的 GLP-1 水平，HIIE 引起了饥饿感的短暂降低，但这两种运动方案都没有影响肥胖男性的 EI。
