Department of Medicine, Federal University of São Paulo, São Paulo, SP, Brazil.
Department of Physical Therapy, São Paulo State University, Presidente Prudente, SP, Brazil.
Biomed Res Int. 2018 May 29;2018:9573630. doi: 10.1155/2018/9573630. eCollection 2018.
This study addresses evidence concerning elastic tubing resistance training (ET) on autonomic modulation in patients with chronic obstructive pulmonary disease (COPD). Autonomic dysfunction is common in COPD and contributes to the development of arrhythmias and sudden death. Along with autonomic dysfunction, muscle dysfunction is related to functional limitations and prognosis of the disease. This study investigated the effects of ET on autonomic modulation, muscle strength, and walking distance in COPD. Subjects were divided into two groups, ET ( = 20; 66,5 ± 8,9 y; 25,5 ± 3,5 kg/m; FEV/FVC: 50,3 ± 11,0) and conventional training ( = 19; 66,0 ± 6,9; 27,1 ± 4,3; FEV/FVC: 55,05 ± 9,56). Both groups undertook 24 sessions for 60 minutes, 3 times in a week. The significance level was ≤ 0,05. Autonomic modulation was evaluated using heart rate variability in the time (rMSSD, ms) and frequency domain (HF, ms). Strength for upper and lower limbs was measured using dynamometry and walking distance was measured using a 6-minute walking test. There were no significant differences in the outcomes between groups. There was an increment to rMSSD [(16,7 ± 11,0 versus 20,8 ± 14,9) versus (14,2 ± 10,0 versus 17,4 ± 12,1)], HF [(141,9 ± 191,3 versus 234,9 ± 335,7) versus (94,1 ± 123,5 versus 177,6 ± 275,5)], shoulder abduction [(50,1 ± 19,6 versus 56,9 ± 20,4) versus (50,5 ± 19,0 versus 56,9 ± 19,3)], knee flexion [(101,9 ± 34,0 versus 116,8 ± 43,3) versus (98,6 ± 21,5 versus 115,1 ± 30,8)], and walking test [(433,0 ± 84,8 versus 468,9 ± 90,8) versus (397,4 ± 99,8 versus 426,3 ± 101,6)] after training for ET and conventional training, respectively. In conclusion, ET improves autonomic modulation in COPD with additional benefits for strength and cardiorespiratory capacity similar to conventional training.
本研究旨在探讨弹性管阻力训练（ET）对慢性阻塞性肺疾病（COPD）患者自主神经调节的影响。自主神经功能障碍在 COPD 中很常见，是心律失常和猝死的重要原因。除自主神经功能障碍外，肌肉功能障碍也与疾病的功能限制和预后有关。本研究探讨了 ET 对 COPD 患者自主神经调节、肌肉力量和步行距离的影响。受试者分为两组，ET 组（=20；66.5±8.9 岁；25.5±3.5kg/m2；FEV/FVC：50.3±11.0）和常规训练组（=19；66.0±6.9；27.1±4.3；FEV/FVC：55.05±9.56）。两组均进行 24 次 60 分钟、每周 3 次的训练。显著性水平为≤0.05。自主神经调节采用心率变异性在时间（rMSSD，ms）和频域（HF，ms）进行评估。上下肢力量采用测力计测量，步行距离采用 6 分钟步行试验测量。两组间结果无显著差异。rMSSD 增加[（16.7±11.0 与 20.8±14.9）与（14.2±10.0 与 17.4±12.1）]、HF 增加[（141.9±191.3 与 234.9±335.7）与（94.1±123.5 与 177.6±275.5）]、肩外展增加[（50.1±19.6 与 56.9±20.4）与（50.5±19.0 与 56.9±19.3）]、膝关节屈曲增加[（101.9±34.0 与 116.8±43.3）与（98.6±21.5 与 115.1±30.8）]、步行试验增加[（433.0±84.8 与 468.9±90.8）与（397.4±99.8 与 426.3±101.6）]，分别为 ET 和常规训练后。总之，ET 改善 COPD 患者的自主神经调节，在改善力量和心肺功能方面的效果与常规训练相似。
