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时间旅行:从果蝇的生物钟突变体到人类的昼夜节律紊乱(诺奖演讲)。

Time Travels: A 40-Year Journey from Drosophila's Clock Mutants to Human Circadian Disorders (Nobel Lecture).

机构信息

Laboratory of Genetics, The Rockefeller University, 1230 York Avenue, New York, NY, 10065, USA.

出版信息

Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11532-11539. doi: 10.1002/anie.201803337. Epub 2018 Jul 13.

DOI:10.1002/anie.201803337
PMID:30003624
Abstract

Living organisms have a biological clock that helps to prepare our physiology for the fluctuations of the day. Key research to elucidate the biological mechanisms of this regular adaptation, referred to as the circadian rhythm, is described by M. W. Young in his Nobel lecture.

摘要

生物体具有生物钟,有助于使我们的生理机能为一天的波动做好准备。M.W. Young 在他的诺贝尔奖演讲中描述了阐明这种有规律适应的生物学机制(即昼夜节律)的关键研究。

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