Seo Bommie Florence, Choi Ji Seon, Shim Hyung-Sup
Department of Plastic and Reconstructive Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Indian J Pathol Microbiol. 2018 Jul-Sep;61(3):425-427. doi: 10.4103/IJPM.IJPM_446_16.
Intramuscular lipoma is an uncommon variant of lipoma that occurs inside muscle tissue. Pathogenesis is thought to be related to neoplastic activity of mesenchymal stem cells, but there still is not an established theory. This entity can be found in almost all areas of the body, mostly within or in connection with skeletal muscle tissue. We have encountered an atypical intramuscular lipoma located in the epidermal layer of the right thigh of an otherwise healthy 35-year-old female. The superficial, protruding skin mass resembled a sebaceous nevus or skin malignancy but was histologically composed of well-defined adipocytes between a mixture of muscle fibers, corresponding with the diagnosis of intramuscular lipoma. Intramuscular lipoma of the skin has never been reported before; thus, the authors suggest the classification "cutaneous" intramuscular lipoma to describe lesions located in the dermal or epidermal layer.
肌内脂肪瘤是脂肪瘤的一种罕见变体，发生于肌肉组织内。其发病机制被认为与间充质干细胞的肿瘤活性有关，但尚未有定论。该病变几乎可在身体的所有部位发现，大多位于骨骼肌组织内或与骨骼肌组织相关。我们遇到一例非典型肌内脂肪瘤，位于一名35岁健康女性右大腿的表皮层。这个浅表、突出于皮肤的肿物类似皮脂腺痣或皮肤恶性肿瘤，但组织学检查显示由明确的脂肪细胞组成，夹杂在肌纤维之间，符合肌内脂肪瘤的诊断。此前从未有过皮肤肌内脂肪瘤的报道；因此，作者建议将位于真皮层或表皮层的病变分类为“皮肤型”肌内脂肪瘤。
