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一名年轻男性患有伴有广泛淋巴管血管侵犯的精母细胞瘤。

Spermatocytic tumor with extensive lymphovascular invasion in a young male.

作者信息

Chawhan Payal Arvind, Ahluwalia Charanjeet, Ahuja Sana

机构信息

Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

出版信息

Urol Case Rep. 2024 Jul 10;55:102797. doi: 10.1016/j.eucr.2024.102797. eCollection 2024 Jul.

Abstract

Spermatocytic tumors are rare testicular cancers, accounting for less than 1 % of all testicular neoplasms, usually affecting older men. This report details a 35-year-old male with a spermatocytic tumor featuring extensive lymphovascular invasion. The patient had a painless, slow-growing right testicular mass, with normal serum tumor markers. Ultrasound and CT scans suggested malignancy. Post-orchiectomy, histopathology confirmed a spermatocytic tumor with polymorphic cells and lymphovascular invasion. Immunohistochemical staining was positive for SALL4 and CD117, negative for OCT4, AFP, and CD30. The patient underwent chemotherapy and remained recurrence-free for a year, highlighting the need for accurate diagnosis and long-term monitoring.

摘要

精母细胞瘤是一种罕见的睾丸癌,占所有睾丸肿瘤的比例不到1%,通常影响老年男性。本报告详细介绍了一名35岁患有精母细胞瘤且伴有广泛淋巴管侵犯的男性患者。该患者右侧睾丸有无痛、生长缓慢的肿块,血清肿瘤标志物正常。超声和CT扫描提示为恶性肿瘤。睾丸切除术后,组织病理学证实为具有多形性细胞和淋巴管侵犯的精母细胞瘤。免疫组化染色显示SALL4和CD117呈阳性,OCT4、甲胎蛋白和CD30呈阴性。该患者接受了化疗,一年内无复发,强调了准确诊断和长期监测的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2ae/11300907/92a4221df1f3/gr1.jpg

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