Chawhan Payal Arvind, Ahluwalia Charanjeet, Ahuja Sana
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Urol Case Rep. 2024 Jul 10;55:102797. doi: 10.1016/j.eucr.2024.102797. eCollection 2024 Jul.
Spermatocytic tumors are rare testicular cancers, accounting for less than 1 % of all testicular neoplasms, usually affecting older men. This report details a 35-year-old male with a spermatocytic tumor featuring extensive lymphovascular invasion. The patient had a painless, slow-growing right testicular mass, with normal serum tumor markers. Ultrasound and CT scans suggested malignancy. Post-orchiectomy, histopathology confirmed a spermatocytic tumor with polymorphic cells and lymphovascular invasion. Immunohistochemical staining was positive for SALL4 and CD117, negative for OCT4, AFP, and CD30. The patient underwent chemotherapy and remained recurrence-free for a year, highlighting the need for accurate diagnosis and long-term monitoring.
精母细胞瘤是一种罕见的睾丸癌,占所有睾丸肿瘤的比例不到1%,通常影响老年男性。本报告详细介绍了一名35岁患有精母细胞瘤且伴有广泛淋巴管侵犯的男性患者。该患者右侧睾丸有无痛、生长缓慢的肿块,血清肿瘤标志物正常。超声和CT扫描提示为恶性肿瘤。睾丸切除术后,组织病理学证实为具有多形性细胞和淋巴管侵犯的精母细胞瘤。免疫组化染色显示SALL4和CD117呈阳性,OCT4、甲胎蛋白和CD30呈阴性。该患者接受了化疗,一年内无复发,强调了准确诊断和长期监测的必要性。