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基线时血压正常和高血压前期的毛里求斯人患高血压的预测因素:一项队列研究。

Predictors of Hypertension in Mauritians with Normotension and Prehypertension at Baseline: A Cohort Study.

机构信息

Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.

Ministry of Health and Quality of Life, Port Louis 11321, Mauritius.

出版信息

Int J Environ Res Public Health. 2018 Jul 2;15(7):1394. doi: 10.3390/ijerph15071394.

Abstract

Information on the predictors of future hypertension in Mauritians with prehypertension is scant. The aim of this study was to analyze the 5-year and 11-year risk of hypertension and its predictors in people with normotension and prehypertension at baseline in Mauritius in 1987. This was a retrospective cohort study of 883 men and 1194 women of Mauritian Indian and Mauritian Creole ethnicity, aged 25⁻74 years old, free of hypertension at baseline in 1987 with follow-up examinations in 1992 and 1998 using the same methodology. The main outcome was 5- and 11-year risk of hypertension. Odds ratios (OR) and corresponding 95% confidence intervals (CI) were calculated. The 5-year risk of hypertension was 5.4-times higher in people with prehypertension compared with normotensive individuals at baseline. The corresponding odds for prehypertensive people at baseline regarding 11-year hypertension risk was 3.39 (95% CI 2.67⁻4.29) in the adjusted logistic regression models. Being of Creole ethnicity (OR 1.42; 95% CI 1.09⁻1.86) increased the 11-year odds of hypertension compared with the Indian population. It is of importance to screen for people with prehypertension and implement strategies to reduce their systolic blood pressure levels to the recommended levels of 120/80 mmHg. Special attention needs to be given to Mauritians of Creole ethnicity.

摘要

毛里求斯人患有高血压前期的未来高血压预测因素的信息很少。本研究旨在分析毛里求斯在 1987 年基线时正常血压和高血压前期人群中,5 年和 11 年高血压风险及其预测因素。这是一项回顾性队列研究,纳入了 883 名男性和 1194 名毛里求斯印度裔和毛里求斯克里奥尔裔的 25⁻74 岁成年人,他们在 1987 年基线时无高血压,随访检查分别在 1992 年和 1998 年进行,使用相同的方法。主要结局是 5 年和 11 年高血压风险。计算了比值比(OR)及其相应的 95%置信区间(CI)。与基线时正常血压的人相比,高血压前期患者的 5 年高血压风险高 5.4 倍。在调整后的逻辑回归模型中,基线时高血压前期患者 11 年高血压风险的相应比值为 3.39(95%CI 2.67⁻4.29)。克里奥尔人(OR 1.42;95%CI 1.09⁻1.86)与印度裔人群相比,11 年高血压风险的比值增加。对高血压前期患者进行筛查并实施降低收缩压水平至建议水平 120/80mmHg 的策略非常重要。需要特别关注克里奥尔裔毛里求斯人。

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