Imai Kazuo, Tarumoto Norihito, Tachibana Hideyuki, Hanabusa Aya, Sakai Jun, Yokota Kazuhiro, Mimura Toshihide, Maesaki Shigefumi
Department of Infectious Disease and Infection Control, Saitama Medical University, Saitama, Japan; Center for Clinical Infectious Diseases and Research, Saitama Medical University, Saitama, Japan.
Department of Infectious Disease and Infection Control, Saitama Medical University, Saitama, Japan; Center for Clinical Infectious Diseases and Research, Saitama Medical University, Saitama, Japan.
J Infect Chemother. 2020 Jan;26(1):128-131. doi: 10.1016/j.jiac.2019.06.008. Epub 2019 Jul 9.
Streptococcus pyogenes is a rare pathogen that causes endogenous endophthalmitis (EE). A healthy 58-year-old woman was diagnosed with EE secondary to septic arthritis caused by S. pyogenes. She underwent enucleation after hospitalization for 14 days with appropriate antibiotic cover. A literature search for outcomes of this condition revealed reports on only 10 eyes among 8 cases identified: 8 eyes (80%) developed poor visual outcome and 5 eyes (50%) underwent enucleation. There were no cases with immunocompromise. Our case report and literature review suggest the importance of awareness of the occurrence of S. pyogenes infection in immunocompetent hosts, and thus early diagnosis and aggressive treatment may be required to improve visual outcome.
化脓性链球菌是一种引起内源性眼内炎（EE）的罕见病原体。一名58岁健康女性被诊断为继发于化脓性链球菌引起的败血症性关节炎的眼内炎。她在接受了14天的适当抗生素治疗后住院并接受了眼球摘除术。对该疾病预后的文献检索显示，在8例确诊病例中仅报道了10只眼：8只眼（80%）视力预后较差，5只眼（50%）接受了眼球摘除术。没有免疫功能低下的病例。我们的病例报告和文献综述表明，认识到免疫功能正常宿主中发生化脓性链球菌感染的重要性，因此可能需要早期诊断和积极治疗以改善视力预后。
