Medical Biophysics Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Fabrication Technology Research Department, Advanced Technology and New Materials Research Institute (ATNMRI), City of Scientific Research and Technology Applications (SRTA-City), Alexandria 21934, Egypt.
Ecotoxicol Environ Saf. 2018 Oct 30;162:354-364. doi: 10.1016/j.ecoenv.2018.07.016. Epub 2018 Jul 11.
Safety of drinking-water is an urgent for human health. It is critical to promote the cheap technologies for water purification to guarantee the free-pathogens-drinking water. The present study has been investigated the antibacterial activity of polyacrylonitrile (PAN) nanofibers membranes which decorated by Ag, CuO or ZnO nanoparticles as bactericides. The hybrid nanofiber composites were fabricated by electrospinning technique and the obtained membranes were characterized using SEM, EDX and FTIR. Their antibacterial activity was evaluated against E. coli and S. aureus. The data was revealed that the functionalization was successfully obtained by the incorporation of nanoparticles as an additive into the polymer solution which associated many superior properties. Continuous PAN membrane fibers with average diameters from 170 to 250 nm without any beads of plain and its hybrid membrane composites were obtained. The antimicrobial activity was estimated using both disk diffusion tests and growth kinetic models. The antibacterial activity was improved as the concentrations of nanoparticles enhanced. This study provided the real solution for production and inactivation of bacteria which related to the impregnated the PAN nanofibers membrane with Ag, CuO or ZnO NPs. The results have significant implications for finding a safe and an inexpensive path to solve the problems of drinking water, especially in the developing countries.
饮用水安全是人类健康的当务之急。推广廉价的水净化技术对于保障无病原体饮用水至关重要。本研究调查了负载银、氧化铜或氧化锌纳米颗粒的聚丙烯腈（PAN）纳米纤维膜作为杀菌剂的抗菌活性。通过静电纺丝技术制备了杂化纳米纤维复合材料，并通过 SEM、EDX 和 FTIR 对其进行了表征。评估了它们对大肠杆菌和金黄色葡萄球菌的抗菌活性。数据表明，通过将纳米颗粒作为添加剂掺入聚合物溶液中，成功地实现了功能化，这与许多优异的性能有关。连续的 PAN 膜纤维具有 170 至 250nm 的平均直径，没有任何珠状结构，并且获得了其杂化膜复合材料。通过圆盘扩散试验和生长动力学模型评估了抗菌活性。随着纳米颗粒浓度的增加，抗菌活性得到了提高。这项研究为生产和灭活与负载银、氧化铜或氧化锌纳米颗粒的 PAN 纳米纤维膜相关的细菌提供了实际的解决方案。这些结果对于寻找一种安全且廉价的方法来解决饮用水问题具有重要意义，特别是在发展中国家。
