抗菌药物管理计划对一家社区教学医院医疗相关感染率的影响。
Impact of an antimicrobial stewardship program on healthcare-associated rates at a community-based teaching hospital.
作者信息
Moffa Matthew A, Walsh Thomas L, Tang Amy, Bremmer Derek N
机构信息
Department of Medicine and Division of Infectious Diseases, Western Pennsylvania Hospital, Pittsburgh, PA, USA.
Department of Medicine and Division of Infectious Diseases, Allegheny General Hospital Pittsburgh, PA, USA.
出版信息
J Infect Prev. 2018 Jul;19(4):191-194. doi: 10.1177/1757177418767760. Epub 2018 May 19.
Abstract
We conducted a pre-intervention/post-intervention study to assess the rate of healthcare-associated infections (HA-CDI) before and after the implementation of an antimicrobial stewardship program (ASP). Upon implementation of our ASP, the usage of targeted antimicrobials, including ceftriaxone, clindamycin, fluoroquinolones and carbapenem antibiotics, were significantly reduced. There was also a significant reduction in HA-CDI/1000 patient-days following ASP implementation (0.84 vs. 0.28; = 0.035).
摘要
我们开展了一项干预前/干预后研究，以评估抗菌药物管理计划（ASP）实施前后医疗保健相关感染（HA-CDI）的发生率。在实施我们的ASP后，包括头孢曲松、克林霉素、氟喹诺酮类和碳青霉烯类抗生素在内的目标抗菌药物的使用量显著减少。在实施ASP后，每1000个患者日的HA-CDI也显著降低（0.84对0.28；P = 0.035）。
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