Rusiniak Mateusz, Wróbel Andrzej, Cieśla Katarzyna, Pluta Agnieszka, Lewandowska Monika, Wójcik Joanna, Skarżyński Piotr Henryk, Wolak Tomasz
Bioimaging Research Center, World Hearing Center of the Institute of Physiology and Pathology of Hearing, Warsaw/Kajetany, Poland;
Department of Neurophysiology, Nencki Institute of Experimental Biology, Polish Academy of Science, Warsaw, Poland.
Acta Neurobiol Exp (Wars). 2018;78(2):92-113.
Alpha rhythm, described by Hans Berger, is mainly recorded from the occipital cortex (OCC) of relaxed subjects with their eyes closed.Early studies indicated the thalamo‑cortical circuit as the origin of alpha rhythm. Recent works suggest an additional relationship between alpha rhythm and the Default Mode Network (DMN). We simultaneously recorded electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) signals in 36 young males asked to alternately close and open their eyes in 30‑s blocks. Using an EEG source channel montage (the recorded signal was interpolated to designated source positions corresponding to certain brain regions) we found an alpha rhythm sub‑activity composed of its intrinsic events, called alpha bursting segments (ABS). More ABS were observed on source channels related to the DMN than those located over the OCC. Similarly, both the beamformer source analysis and fMRI indicated that the specific ABS activity detected on the posterior cingulate cortex/precuneus (PCC) source channel was less related to the OCC than to the DMN source channels. The fMRI analysis performed using the PCC‑ABS as a general linear model regressor indicated an increased blood oxygenation level‑dependent signal change in DMN nodes - precuneus and prefrontal cortex. These results confirm the OCC source of alpha activity a nd additional specific sources of ABS in the DMN.
由汉斯·伯杰所描述的阿尔法节律，主要是在闭眼放松的受试者的枕叶皮质（OCC）记录到的。早期研究表明丘脑-皮质回路是阿尔法节律的起源。最近的研究表明阿尔法节律与默认模式网络（DMN）之间存在额外的关系。我们让36名年轻男性以30秒为一个时间段交替闭眼和睁眼，同时记录他们的脑电图（EEG）和功能磁共振成像（fMRI）信号。使用脑电图源通道蒙太奇（将记录的信号内插到对应于特定脑区的指定源位置），我们发现了一种由其内在事件组成的阿尔法节律子活动，称为阿尔法爆发段（ABS）。在与默认模式网络相关的源通道上观察到的ABS比位于枕叶皮质上的更多。同样，波束形成器源分析和功能磁共振成像均表明，在后扣带回皮质/楔前叶（PCC）源通道上检测到的特定ABS活动与枕叶皮质的相关性小于与默认模式网络源通道的相关性。使用PCC-ABS作为一般线性模型回归器进行的功能磁共振成像分析表明，默认模式网络节点——楔前叶和前额叶皮质中依赖血氧水平的信号变化增加。这些结果证实了阿尔法活动的枕叶皮质源以及默认模式网络中ABS的额外特定源。
