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北京大学泌尿外科研究所前列腺切除术评分:一种简单的前列腺癌术前分类方法,可预测手术难度和风险。

The Institute of Urology, Peking University prostatectomy score: a simple preoperative classification of prostate cancer for predicting surgical difficulty and risk.

机构信息

Department of Urology, Peking University First Hospital and Institute of Urology, Peking University, Beijing 100034, China.

出版信息

Asian J Androl. 2018 Nov-Dec;20(6):581-586. doi: 10.4103/aja.aja_39_18.

Abstract

Traditional laparoscopic radical prostatectomy is a treatment choice in many developing countries and regions for most patients with localized prostate cancer; however, no system for predicting surgical difficulty and risk has been established. This study aimed to propose a simple and standard preoperative classification system of prostate cancer using preoperative data to predict surgical difficulty and risk and to evaluate the relationship between the data and postoperative complications. We collected data from 236 patients and divided them into three groups to evaluate and validate the relationships among preoperative, operative, and postoperative data. This new scoring system is based on the body mass index, ultrasonic prostate volume, preoperative prostate-specific antigen level, middle lobe protrusion, and clinical stage. In the scoring group, we classified 89 patients into two groups: the low-risk group (score of <4) and high-risk group (score of ≥4), and then compared the postoperative data between the two groups. The positive surgical margin rate was higher in the high-risk group than low-risk group. The results in validation Groups A and B were similar to those in the scoring group. The focus of our scoring system is to allow for preliminary assessment of surgical difficulty by collecting the patients' basic information. Urologists can easily use the scoring system to evaluate the surgical difficulty and predict the risks of a positive surgical margin and urinary incontinence in patients undergoing laparoscopic radical prostatectomy.

摘要

传统的腹腔镜前列腺根治术是许多发展中国家和地区治疗局限性前列腺癌患者的选择方法;然而,尚未建立预测手术难度和风险的系统。本研究旨在提出一种简单而标准的前列腺癌术前分类系统,使用术前数据预测手术难度和风险,并评估数据与术后并发症之间的关系。我们收集了 236 例患者的数据,并将其分为三组进行评估和验证,以验证术前、术中及术后数据之间的关系。该新评分系统基于体重指数、超声前列腺体积、术前前列腺特异性抗原水平、中叶突出和临床分期。在评分组中,我们将 89 例患者分为两组:低危组(评分<4)和高危组(评分≥4),然后比较两组的术后数据。高危组的阳性切缘率高于低危组。验证组 A 和 B 的结果与评分组相似。我们评分系统的重点是通过收集患者的基本信息,对手术难度进行初步评估。泌尿科医生可以轻松使用评分系统评估手术难度,并预测腹腔镜前列腺根治术患者阳性切缘和尿失禁的风险。

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