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滥交女性中巨细胞病毒（CMV）和单纯疱疹病毒感染的流行病学：不存在CMV的外源性再感染。

Epidemiology of infections with cytomegalovirus (CMV) and herpes simplex virus in promiscuous women: absence of exogenous reinfection with CMV.

作者信息

Wertheim P, Galama J, Geelen J, Buurman C, van der Noordaa J

出版信息

Genitourin Med. 1985 Dec;61(6):383-6. doi: 10.1136/sti.61.6.383.

DOI:10.1136/sti.61.6.383
PMID:3002963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1011865/
Abstract

Herpes simplex virus (HSV) was shed from the genital tracts of 26 (15%) and cytomegalovirus (CMV) from 19 (11%) of 177 promiscuous women. Virus excretion was especially common (HSV 41% and CMV 19%) in the youngest age group (aged 19 or less). Episodic shedding of CMV was studied by restriction enzyme analysis of the viral DNAs prepared from repeat isolates. Repeat isolates from each woman were identical, which indicated that recurrent shedding of CMV resulted from endogenous reinfection. Even under conditions of high exposure no exogenous reinfection with CMV could be shown, which indicated that exogenous reinfection is rare.

摘要

在177名性乱交女性中，26人（15%）的生殖道排出单纯疱疹病毒（HSV），19人（11%）排出巨细胞病毒（CMV）。病毒排出在最年轻年龄组（19岁及以下）尤为常见（HSV为41%，CMV为19%）。通过对重复分离株制备的病毒DNA进行限制性酶切分析，研究了CMV的间歇性排出。来自每位女性的重复分离株是相同的，这表明CMV的反复排出是由内源性再感染引起的。即使在高暴露条件下，也未显示有CMV的外源性再感染，这表明外源性再感染很少见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e59/1011865/57ff458d7238/genitmed00078-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e59/1011865/57ff458d7238/genitmed00078-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e59/1011865/57ff458d7238/genitmed00078-0035-a.jpg

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本文引用的文献

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J Infect Dis. 1984 Apr;149(4):645-6. doi: 10.1093/infdis/149.4.645.
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Transmission of cytomegalovirus by renal allograft demonstrated by restriction enzyme analysis.通过限制性内切酶分析证实巨细胞病毒经同种异体肾移植传播。
Lancet. 1983 Apr 30;1(8331):980-1. doi: 10.1016/s0140-6736(83)92098-6.
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Inapparent genital herpes simplex infection in women attending a venereal disease clinic.
Sex Transm Dis. 1984 Apr-Jun;11(2):91-3. doi: 10.1097/00007435-198404000-00008.
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Association of cervical cytomegaloviruses with venereal disease.宫颈巨细胞病毒与性病的关联。
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Am J Epidemiol. 1972 May;95(5):483-9. doi: 10.1093/oxfordjournals.aje.a121415.
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Demonstration of exogenous genital reinfection with herpes simplex virus type 2 by restriction endonuclease fingerprinting of viral DNA.
J Infect Dis. 1979 Sep;140(3):295-304. doi: 10.1093/infdis/140.3.295.
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Cytomegalovirus in female patients attending a VD clinic.性病门诊女性患者中的巨细胞病毒
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