Knox G E, Pass R F, Reynolds D W, Stagno S, Alford C A
J Infect Dis. 1979 Sep;140(3):419-22. doi: 10.1093/infdis/140.3.419.
The prevalence of subclinical infections caused by cytomegaloviruses (CMV) and herpes simplex viruses (HSV) was assessed simultaneously in the genital and urinary tracts of 1,101 indigent women. Shedding of CMV from the genital and urinary tracts exceeded that of HSV by ninefold (8.89% vs. 0.95) and sevenfold (3.8% vs. 0.51%), respectively. Pregnancy, regardless of gestational age, had no discernible influence on productive infection with either virus in either the genital or the urinary tract. In contrast, age was a significant variable, especially with CMV. The prevalence of CMV shedding decreased steadily with age, from peak values of 15% and 8% in the genital and urinary tracts, respectively, of females 11-14 years of age to undetectable levels in females 31 years of age and older. Productive HSV infection was more prevalent in postmenopausal than in premenopausal women: 2.4% vs. 0.8% and 3.1% vs. 0.2% in the genital and urinary tracts, respectively. Likewise, HSV infection of both the genital and the urinary tract combined was more common in older than in younger females.
在1101名贫困女性的生殖道和泌尿道中，同时评估了由巨细胞病毒（CMV）和单纯疱疹病毒（HSV）引起的亚临床感染的患病率。CMV在生殖道和泌尿道中的脱落率分别比HSV高出9倍（8.89%对0.95%）和7倍（3.8%对0.51%）。妊娠，无论孕周如何，对生殖道或泌尿道中任何一种病毒的活动性感染均无明显影响。相比之下，年龄是一个显著变量，尤其是对于CMV。CMV脱落率随年龄稳步下降，从11 - 14岁女性生殖道和泌尿道中分别高达15%和8%的峰值，降至31岁及以上女性中检测不到的水平。HSV活动性感染在绝经后女性中比绝经前女性更普遍：在生殖道和泌尿道中分别为2.4%对0.8%和3.1%对0.2%。同样，生殖道和泌尿道联合感染HSV在老年女性中比年轻女性更常见。
