SPLINT：用于分析一维电泳凝胶中片段大小的三次样条插值程序。
SPLINT: a cubic spline interpolation program for the analysis of fragment sizes in one-dimensional electrophoresis gels.
作者信息
Gariepy C E, Lomax M I, Grossman L I
出版信息
Nucleic Acids Res. 1986 Jan 10;14(1):575-81. doi: 10.1093/nar/14.1.575.
Abstract
SPLINT (SPLine INTerpolation) is a BASIC microcomputer program that uses electrophoretic data on the migration distances of DNA fragments of known size to approximate the relationship between distance moved and DNA fragment size by a piecewise cubic spline function. This function places all standards exactly on the calibration curve and then determines from it the sizes of other fragments in the gel. Special advantages of this program include the use of a digitizer to enter the fragment positions directly from a gel photograph and the optional generation of a graph of the approximating function plus the placement on it of points from any specified gel lanes.
摘要
SPLINT（样条插值法）是一个用已知大小的DNA片段迁移距离的电泳数据，通过分段三次样条函数来近似迁移距离与DNA片段大小之间关系的BASIC微机程序。该函数将所有标准片段精确地置于校准曲线上，然后据此确定凝胶中其他片段的大小。这个程序的特殊优势包括使用数字化仪直接从凝胶照片输入片段位置，以及可选择生成近似函数的图表，并在其上标注来自任何指定凝胶泳道的点。
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Apple software for analysis of the size of restriction fragments.用于分析限制性片段大小的苹果软件。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):689-94. doi: 10.1093/nar/12.1part2.689.
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DNAGEL: a computer program for determining DNA fragment sizes using a small computer equipped with a graphics tablet.DNAGEL：一种计算机程序，用于使用配备图形输入板的小型计算机确定DNA片段大小。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):679-88. doi: 10.1093/nar/12.1part2.679.
7
GELYSIS: Pascal-implemented analysis of one-dimensional electrophoresis gels.凝胶分析：用Pascal语言实现的一维电泳凝胶分析。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):493-8. doi: 10.1093/nar/12.1part2.493.
8
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