Grillner L, Broberger U, Chrystie I, Ransjö U
Scand J Infect Dis. 1985;17(4):349-55. doi: 10.3109/13813458509058774.
An outbreak of rotavirus infections among newborns at Karolinska Hospital, Stockholm, which has been going on for greater than 2 years has been followed with clinical and epidemiological investigations. About one third of the babies born in the hospital were infected at the age of 3 days. The clinical symptoms were mild, 8.8% of the rotavirus positive babies had loose stools compared to 1.9% of those who did not excrete the virus. An epidemiological survey in the neonatal intensive care unit suggested that rotavirus was introduced into the unit by babies admitted from the obstetric wards. The main reservoir of rotavirus was the babies and rotavirus was not found among staff or mothers. In the beginning hygienic measures seemed to be effective but after some weeks the colonization rate again increased. Electropherotyping of samples collected during different periods showed that one single rotavirus electropherotype belonging to the subgroup 1 of human rotavirus was found throughout the outbreak.
斯德哥尔摩卡罗林斯卡医院新生儿中爆发的轮状病毒感染已经持续了两年多，随后进行了临床和流行病学调查。该医院约三分之一的新生儿在3天时受到感染。临床症状较轻，轮状病毒呈阳性的婴儿中有8.8%出现腹泻，而未排出该病毒的婴儿中这一比例为1.9%。新生儿重症监护病房的一项流行病学调查表明，轮状病毒是由产科病房收治的婴儿带入该病房的。轮状病毒的主要储存宿主是婴儿，在医护人员或母亲中未发现轮状病毒。起初，卫生措施似乎有效，但几周后定植率再次上升。对不同时期采集的样本进行的电泳分型显示，在整个疫情期间均发现了一种单一的属于人类轮状病毒亚组1的轮状病毒电泳型。
