Perera Marisa J, Reina Samantha A, Elfassy Tali, Potter JoNell E, Sotres Alvarez Daniela, Simon Melissa A, Isasi Carmen R, Stuebe Alison M, Schneiderman Neil, Llabre Maria M
a Department of Psychology , University of Miami , Coral Gables , Florida , USA.
b Miller School of Medicine , University of Miami , Coral Gables , Florida , USA.
Women Health. 2019 May-Jun;59(5):481-495. doi: 10.1080/03630242.2018.1500415. Epub 2018 Aug 9.
To compare cardiovascular risk and disease prevalence in U.S. Hispanics/Latinas with and without a history of gestational diabetes mellitus (GDM). Cross-sectional data from 2008 to 2011 were analyzed for 8,262 (305 with GDM history) parous women, aged 20-73 years, from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Women with and without a history of GDM were compared on sociodemographic, cardiovascular risk factor, and disease data from standardized interviews and fasting blood tests, using chi-square tests, t-tests, and logistic regressions to determine odds ratios (ORs) and 95 percent confidence intervals (CIs). Adjusting for covariates, compared to those without a history of GDM, women with a history of GDM were younger (M = 39.1 years [95 percent CI = 37.8, 41.6] vs. 45.5 years [95 percent CI = 44.9, 46.1]) and more likely to have health insurance (68.1 percent [95 percent CI = 60.3 percent, 76.0 percent] vs. 54.9 percent [95 percent CI = 52.8 percent, 57.1 percent]), had greater waist circumference (M = 102.3 cm, [95 percent CI = 100.2, 104.3] vs. 98.1 cm [95 percent CI = 97.4, 98.5]) and higher fasting glucose (116.0 mg/dL [95 percent CI = 107.8, 124.3] vs. 104.2 mg/dL [95 percent CI = 103.4, 105.1]), and had higher odds of having metabolic syndrome (OR = 1.7 [95 percent CI = 1.2, 2.6]) or diabetes (OR = 3.3 [95 percent CI = 2.2, 4.8]). Prevalences of heart and cerebrovascular disease were similar. GDM history was positively associated with diabetes but not with cardiovascular disease.
比较有和没有妊娠期糖尿病（GDM）病史的美国西班牙裔/拉丁裔女性的心血管疾病风险和患病率。对西班牙裔社区健康研究/拉丁裔研究（HCHS/SOL）中8262名（305名有GDM病史）年龄在20 - 73岁的经产妇2008年至2011年的横断面数据进行了分析。根据标准化访谈和空腹血液检测得到的社会人口统计学、心血管危险因素和疾病数据，对有和没有GDM病史的女性进行比较，使用卡方检验、t检验和逻辑回归来确定比值比（OR）和95%置信区间（CI）。在对协变量进行调整后，与没有GDM病史的女性相比，有GDM病史的女性更年轻（平均年龄M = 39.1岁[95%CI = 37.8, 41.6] 对比45.5岁[95%CI = 44.9, 46.1]），更有可能拥有医疗保险（68.1% [95%CI = 60.3%, 76.0%] 对比54.9% [95%CI = 52.8%, 57.1%]），腰围更大（平均M = 102.3厘米，[95%CI = 100.2, 104.3] 对比98.1厘米[95%CI = 97.4, 98.5]），空腹血糖更高（116.0毫克/分升[95%CI = 107.8, 124.3] 对比104.2毫克/分升[95%CI = 103.4, 105.1]），并且患代谢综合征（OR = 1.7 [95%CI = 1.2, 2.6]）或糖尿病（OR = 3.3 [95%CI = 2.2, 4.8]）的几率更高。心脏和脑血管疾病的患病率相似。GDM病史与糖尿病呈正相关，但与心血管疾病无关。
