含酪蛋白磷酸肽无定形磷酸钙与不含酪蛋白磷酸肽无定形磷酸钙的氟化物清漆对乳牙再矿化作用的比较。

Comparison of remineralization by fluoride varnishes with and without casein phosphopeptide amorphous calcium phosphate in primary teeth.

作者信息

Salman Nehal Raid, ElTekeya Magda, Bakry Niveen, Omar Samia Soliman, El Tantawi Maha

机构信息

a Department of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry , Pharos University , Alexandria , Egypt.

b Department of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry , Alexandria University , Alexandria , Egypt.

出版信息

Acta Odontol Scand. 2019 Jan;77(1):9-14. doi: 10.1080/00016357.2018.1490967. Epub 2018 Jul 25.

DOI:10.1080/00016357.2018.1490967

PMID:30045657

Abstract

OBJECTIVE

To compare MI (5% NaF with 2% CPP-ACP) and Prevident (5% NaF) varnishes in remineralizing caries-like lesions in primary teeth regarding calcium and phosphate enamel content and lesion depth.

MATERIAL AND METHODS

Caries-like lesions were created in 48 primary teeth which were divided into 2 halves; one left untreated (control) and the other half treated with MI or Prevident varnishes. Calcium and phosphate content was assessed using energy dispersive X-ray spectrometer and reduction in lesion depth was assessed using polarized light microscopy. Demineralization and remineralization values in each group were compared using paired t test and percentage change between groups was compared using t test and Mann Whitney U test.

RESULTS

A greater percentage increase of calcium was observed in MI than Prevident specimens (median = 8.97 and 2.67, p < .0001), with greater calcium phosphate ratio percentage increase (median = 28.96 and 7.40) and phosphate percentage reduction (median = 15.5 and 4.51). The mean (SD) percentages reduction in lesion depth in the MI varnish was significantly greater than in Prevident varnish (44.41 (7.12) and 22.73 (9.35), p < .0001).

CONCLUSIONS

MI varnish had better remineralization effect in primary teeth than Prevident varnish in terms of higher mineral content and shallower lesion depth.

摘要

目的

比较含5%氟化钠与2%酪蛋白磷酸肽 - 无定形磷酸钙（MI）的护齿剂和含5%氟化钠的Prevident护齿剂对乳牙龋样病变进行再矿化时牙釉质中钙和磷的含量以及病变深度的影响。

材料与方法

在48颗乳牙上制备龋样病变，将每颗牙齿分为两半；一半不做处理（对照），另一半用MI或Prevident护齿剂处理。使用能量色散X射线光谱仪评估钙和磷的含量，使用偏光显微镜评估病变深度的减小情况。使用配对t检验比较每组中的脱矿和再矿化值，使用t检验和曼 - 惠特尼U检验比较组间的百分比变化。

结果

与Prevident样本相比，MI样本中观察到钙的百分比增加更大（中位数分别为8.97和2.67，p <.0001），磷酸钙比例的百分比增加更大（中位数分别为28.96和7.40），磷的百分比降低更大（中位数分别为15.5和4.51）。MI护齿剂组病变深度减小的平均（标准差）百分比显著大于Prevident护齿剂组（44.41（7.12）和22.73（9.35），p <.0001）。