Meunier J, Cavanagh P
Biol Cybern. 1986;53(3):159-71. doi: 10.1007/BF00342884.
An associative memory is modeled in networks of cells that are assumed to have the short-term plasticity of the neuromuscular junction of the frog. The data relating synaptic transmission efficiency and stimulation frequency for post-tetanic potentiation of the neuromuscular junction are represented by polynomial expansions. Simulation of storage and retrieval demonstrates that functional associative memory is feasible based on this particular synaptic plasticity. Retrieval reaches a maximum efficiency at a delay of three minutes after storage and is lost after about 9 min. The signal to noise ratio of the retrieved pattern drops steadily as additional associations are stored in memory but retrieval appears to be possible with up to four stored associations. Although the data are derived from synapses not normally proposed as a basis for memory functions, the results here will generalize to other synaptic junctions located more centrally that have similar characteristics. This simulation technique allows the efficiency of associative memory based on various types of synaptic plasticity to be evaluated.
关联记忆是在假设具有青蛙神经肌肉接头短期可塑性的细胞网络中建模的。与神经肌肉接头强直后增强的突触传递效率和刺激频率相关的数据由多项式展开表示。存储和检索的模拟表明，基于这种特定的突触可塑性，功能性关联记忆是可行的。检索在存储后三分钟的延迟时达到最大效率，并在大约9分钟后消失。随着更多关联存储在记忆中，检索模式的信噪比稳步下降，但似乎最多存储四个关联时仍可进行检索。尽管这些数据来自通常不被认为是记忆功能基础的突触，但这里的结果将推广到位于更中枢位置且具有相似特征的其他突触连接。这种模拟技术允许评估基于各种类型突触可塑性的关联记忆的效率。
