Donoghue J P, Herkenham M
Brain Res. 1986 Feb 19;365(2):397-403. doi: 10.1016/0006-8993(86)91658-6.
A number of recent studies have demonstrated two chemically distinct compartments in the neostriatum: opiate receptor-rich patches and a surrounding matrix. Using axonal transport and receptor localization techniques in the rat brain, we have found that striatal projections from architectonically distinct cortical fields conform to this compartmentalized plan. The prelimbic cortex has bilateral projections that concentrate within the striatal patches. In contrast, the agranular motor cortex and cingulate cortex have bilateral projections to the matrix, while the somatic sensory cortex and visual cortex have ipsilateral matrix projections. Each matrix input occupies a characteristic striatal district. The projection to the patches distributes prelimbic input throughout the striatum, which may allow for prelimbic interactions with input from all other cortical areas.
最近的一些研究表明，新纹状体存在两个化学性质不同的区域：富含阿片受体的斑块和周围的基质。利用大鼠脑中的轴突运输和受体定位技术，我们发现，来自结构不同的皮质区域的纹状体投射符合这种分区模式。前边缘皮质有双侧投射，集中在纹状体斑块内。相比之下，无颗粒运动皮质和扣带回皮质有双侧投射到基质，而躯体感觉皮质和视觉皮质有同侧基质投射。每个基质输入占据一个特征性的纹状体区域。投射到斑块的纤维将前边缘皮质的输入分布于整个纹状体，这可能使前边缘皮质能够与来自所有其他皮质区域的输入进行相互作用。
