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来自……心材的具有细胞毒性的倍半萜类化合物 。 你提供的原文似乎不完整,句末的“.”应补充完整的信息,以便更准确地理解和翻译。

Sesquiterpenoids with cytotoxicity from heartwood of .

作者信息

Meng Hui, Chen De-Li, Yang Yun, Liu Yang-Yang, Wei Jian-He

机构信息

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing , China.

Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine, Hainan Branch Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College , Haikou , China.

出版信息

J Asian Nat Prod Res. 2019 Oct;21(10):954-960. doi: 10.1080/10286020.2018.1490727. Epub 2018 Jul 26.

Abstract

Two new sesquiterpenoids, named dalodorin A () and dalodorin B (), together with four known sesquiterpenoids, were isolated from the heartwood of . Their structures were elucidated on the basis of spectroscopic analysis including 1D and 2D NMR techniques and HR-ESI-MS. Evaluation of the isolated compounds for cytotoxicity against two human cancer cell lines (Hela and HepG-2) showed moderate activities (25.22-60.45 μM).

摘要

从[植物名称]的心材中分离出两种新的倍半萜类化合物,命名为达洛多灵A()和达洛多灵B(),以及四种已知的倍半萜类化合物。基于包括一维和二维核磁共振技术以及高分辨电喷雾电离质谱在内的光谱分析阐明了它们的结构。对分离出的化合物针对两种人类癌细胞系(Hela和HepG - 2)的细胞毒性进行评估,结果显示具有中等活性(25.22 - 60.45 μM)。

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