从降香黄檀精油中分离得到的生物活性倍半萜。
Bioactive sesquiterpenes isolated from the essential oil of Dalbergia odorifera T. Chen.
机构信息
Institute of Pharmaceutical Informatics, Zhejiang University, Zijingang, Hangzhou, PR China.
出版信息
Fitoterapia. 2010 Jul;81(5):393-6. doi: 10.1016/j.fitote.2009.11.012. Epub 2009 Dec 4.
Investigation of the essential oil from the heartwood of Dalbergia odorifera T. Chen afforded the sesquiterpenes 1 and 2, that both showed anti-platelet activity. Their backbones were totally the same only with subtle difference in the chiral centre. Additionally, antithrombotic and anti-platelet activities of these two compounds were measured. The results showed that the antithrombotic activity of these two compounds was poor, while their anti-platelet activity was strong at middle and high concentrations.
从降香的心材中提取的精油中分离得到了两种倍半萜 1 和 2，它们都具有抗血小板活性。它们的骨架完全相同，只是手性中心略有不同。此外，还测量了这两种化合物的抗血栓形成和抗血小板活性。结果表明，这两种化合物的抗血栓形成活性较差，而在中高浓度时具有较强的抗血小板活性。
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