Gaudre Noémie, Madani L Y, Badiaga Youssouf, Dembele Abdoul Karim, Bathily Moussa, Kone Abdrahamane, Diallo Yacouba Lazare, Diallo Dapa Aly
Mali Med. 2013;28(3):39-44.
Epidemiological, clinical and biological characteristics of colorectal cancer vary across continents probably because of different risk factors that are not yet fully listed in countries with limited resources. This study describes the epidemiological and clinical features of colorectal cancer at a University hospital in Bamako, Mali.
A retrospective study that concerned the period from 2005 to 2011 was carried out. It included records of patients with colorectal cancer histologically documented in the service. Were analyzed epidemiological, clinical and biological data stored in files.
One hundred-thirteen (113) cases of colorectal cancer were diagnosed representing 15% of all cancers documented over the 7 years. The number of cases increased year by year. The cases of colorectal cancer are not uncommon in young patients (23% under 30 years of age, 60% under 50). The male is significantly more represented in this population of colorectal carriers with a sex ratio M / F = 2. The time between first the symptom and care is long and the diagnosis is made in 85% of cases at a metastatic stage. Localization of the cancer is more frequent in the colon (56%) than in the rectum (44%). Cancer is an adenocarcinoma in 97% of cases.
These epidemiological and clinical features invite practitioners to reconsider the concept of rarity of colorectal cancer in Africa and vigilance in front of a digestive disorder, even the patient is young, they also emphasize the need to conduct prospective studies to identify specific risk factors and develop appropriate strategies for the prevention and treatment of colorectal cancer in Mali.
由于资源有限的国家尚未完全列出不同的风险因素,结直肠癌的流行病学、临床和生物学特征在各大洲有所不同。本研究描述了马里巴马科一家大学医院结直肠癌的流行病学和临床特征。
开展了一项回顾性研究,涉及2005年至2011年期间。研究纳入了该科室组织学确诊的结直肠癌患者记录。对档案中存储的流行病学、临床和生物学数据进行了分析。
共诊断出113例结直肠癌病例,占7年期间所有确诊癌症病例的15%。病例数逐年增加。结直肠癌在年轻患者中并不罕见(23%年龄在30岁以下,60%年龄在50岁以下)。在结直肠癌患者群体中,男性占比显著更高,男女比例为2。从出现症状到就医的时间较长,85%的病例在转移阶段才得以确诊。癌症在结肠的定位比在直肠更常见(56%对44%)。97%的病例为腺癌。
这些流行病学和临床特征促使从业者重新审视非洲结直肠癌罕见的观念,并对消化系统疾病保持警惕,即使患者很年轻;它们还强调需要开展前瞻性研究,以确定特定风险因素,并制定适合马里结直肠癌预防和治疗的策略。