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母亲碘过量:后天性新生儿甲状腺功能减退症的罕见病因。

Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism.

作者信息

Hamby Tyler, Kunnel Nayana, Dallas John S, Wilson Don P

机构信息

Department of Research Operations, Cook Children's Medical Center, 801 7th Ave., Fort Worth, TX 76104, USA.

Texas College of Osteopathic Medicine, University of North Texas Health Science Center, Fort Worth, TX, USA.

出版信息

J Pediatr Endocrinol Metab. 2018 Sep 25;31(9):1061-1064. doi: 10.1515/jpem-2018-0138.

Abstract

Background Excessive iodine exposure is an often overlooked cause of neonatal hypothyroidism. Case presentation We present an infant with iodine-induced hypothyroidism, which was detected at age 15 days by newborn screening. The infant's iodine excess resulted from maternal intake of seaweed soup both during and after pregnancy. Treatment included discontinuation of seaweed soup, temporary interruption of breastfeeding and short-term levothyroxine therapy. By age 4 months, the infant's hypothyroidism had resolved, and her growth and development were normal. Conclusions This case illustrates the importance of considering excess dietary iodine as a possible cause of hypothyroidism in infants.

摘要

背景 碘摄入过量是新生儿甲状腺功能减退症一个常被忽视的病因。病例报告 我们报告一名碘诱发的甲状腺功能减退症婴儿,其在出生后15天通过新生儿筛查被发现。该婴儿碘摄入过量是由于其母亲在孕期及产后摄入紫菜汤所致。治疗措施包括停止食用紫菜汤、暂时中断母乳喂养以及短期左旋甲状腺素治疗。到4个月大时,该婴儿的甲状腺功能减退症已痊愈,其生长发育正常。结论 本病例说明了将饮食中碘过量视为婴儿甲状腺功能减退症可能病因的重要性。

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