Department of Pediatrics, Subdivision of Endocrinology, Willem Alexander Children's Hospital, LUMC, Leiden, The Netherlands
Department of Pediatrics, Subdivision of Endocrinology, Sophia Children's Hospital, Erasmus Medical Centre, Rotterdam, The Netherlands.
BMJ Case Rep. 2021 Feb 19;14(2):e237930. doi: 10.1136/bcr-2020-237930.
Both insufficient and excessive maternal iodine consumption can result in congenital hypothyroidism. In East Asian cultures, seaweed is traditionally consumed in high quantities by peripartum women as it is thought to improve lactation. We present a case of transient congenital hypothyroidism due to maternal seaweed consumption at a daily basis during pregnancy and lactation in a Dutch family without Asian background. This case highlights that even in families of non-Asian background, high maternal intake of iodine-rich seaweed occurs and can result in transient or permanent hyperthyrotropinemia in the neonate with risk of impaired neurodevelopmental outcome if untreated.
母亲碘摄入不足或过量均可导致先天性甲状腺功能减退症。在东亚文化中,海藻被认为可以促进泌乳,因此围产期妇女传统上会大量食用海藻。我们报告了一例荷兰家庭的病例,该家庭无亚洲背景,但母亲在怀孕期间和哺乳期每天都食用海藻,导致新生儿出现短暂性先天性甲状腺功能减退症。该病例提示,即使在非亚洲背景的家庭中,母亲也可能摄入大量富碘海藻,导致新生儿出现暂时性或永久性促甲状腺激素升高,如果不治疗,可能会对神经发育产生不良影响。