Laboudi Majda, Sahibi Hamid, Elabandouni Mohamed, Nhammi Haddou, Ait Hamou Sanaa, Sadak Abderrahim
Department of Parasitology, National Institute of Hygiene, Rabat, Morocco.
Agronomic and Veterinary Institute Hassan II of Rabat (IAV), Rabat, Morocco.
Acta Trop. 2018 Nov;187:275-283. doi: 10.1016/j.actatropica.2018.07.019. Epub 2018 Jul 26.
Leishmaniasis is considered one of the most neglected diseases worldwide. In Morocco, cutaneous leishmaniasis is an important public health problem. Leishmania major and Leishmania tropica are the two major species in this country. Despite all efforts, monitoring and control of the cutaneous leishmaniasis is still challenging. We used for the first time a vertical analysis of the control of cutaneous leishmaniasis in Morocco from the document review and publications. This analysis allowed us to develop an epidemiological model that emphasized key possible interventions. No evaluation studies of these interventions in Morocco were done. Global Evidence underline the effectiveness of preventive interventions produced in integrate inter-sectorial strategy framework (e.g use of insecticide-treated bednets, indoor residual spraying and rodents' control) rather than treatments such as based thermotherapy, cryotherapy, photodynamic therapy, CO2 laser and paromomycin. Therefore, integrated vector management control (IVMC) with communityc participation is recommended as effective strategy. Strengthening of the IVMC with community involvement are necessary conditions to improve the program of cutaneous leishmaniasis and prevent epidemic foci appearance.
利什曼病被认为是全球最被忽视的疾病之一。在摩洛哥,皮肤利什曼病是一个重要的公共卫生问题。硕大利什曼原虫和热带利什曼原虫是该国的两种主要病原体。尽管付出了种种努力,但皮肤利什曼病的监测和控制仍然具有挑战性。我们首次通过文献回顾和出版物对摩洛哥皮肤利什曼病的控制进行了纵向分析。这一分析使我们能够建立一个强调关键可能干预措施的流行病学模型。在摩洛哥尚未对这些干预措施进行评估研究。全球证据强调了在综合部门间战略框架内采取预防性干预措施(如使用经杀虫剂处理的蚊帐、室内滞留喷洒和控制啮齿动物)的有效性,但热疗法、冷冻疗法、光动力疗法、二氧化碳激光和巴龙霉素等治疗方法效果不佳)。因此,建议将社区参与式综合病媒管理控制(IVMC)作为有效策略。加强社区参与式IVMC是改善皮肤利什曼病防治计划、防止疫情热点出现的必要条件。