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基于互联网的认知行为疗法和体育锻炼对抑郁症的成本效益

Cost-effectiveness of internet-based cognitive-behavioural therapy and physical exercise for depression.

作者信息

Kraepelien Martin, Mattsson Simon, Hedman-Lagerlöf Erik, Petersson Ingemar F, Forsell Yvonne, Lindefors Nils, Kaldo Viktor

机构信息

Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Sweden.

Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Sweden.

出版信息

BJPsych Open. 2018 Jul 16;4(4):265-273. doi: 10.1192/bjo.2018.38. eCollection 2018 Jul.

Abstract

BACKGROUND

Both internet-based cognitive-behavioural therapy (ICBT) and physical exercise are alternatives to treatment as usual (TAU) in managing mild to moderate depression in primary care.

AIMS

To determine the cost-effectiveness of ICBT and physical exercise compared with TAU in primary care.

METHOD

Economic evaluation of a randomised controlled trial ( = 945) in Sweden. Costs were estimated by a service use questionnaire and used together with the effects on quality-adjusted life-years (QALYs). The primary 3-month healthcare provider perspective in primary care was complemented by a 1-year societal perspective.

RESULTS

The primary analysis showed that incremental cost per QALY gain was €8817 for ICBT and €14 571 for physical exercise compared with TAU. At the established willingness-to-pay threshold of €21 536 (£20 000) per QALY, the probability of ICBT being cost-effective is 90%, and for physical exercise is 76%, compared with TAU.

CONCLUSIONS

From a primary care perspective, both ICBT and physical exercise for depression are likely to be cost-effective compared with TAU.

DECLARATION OF INTEREST

None.

摘要

背景

在初级保健中管理轻度至中度抑郁症时,基于互联网的认知行为疗法(ICBT)和体育锻炼都是常规治疗(TAU)的替代方案。

目的

确定在初级保健中,与常规治疗相比,ICBT和体育锻炼的成本效益。

方法

对瑞典一项随机对照试验(n = 945)进行经济评估。通过服务使用问卷估算成本,并将其与对质量调整生命年(QALY)的影响结合使用。以初级保健中3个月的医疗保健提供者视角为主,并辅以1年的社会视角。

结果

初步分析表明,与常规治疗相比,ICBT每获得一个QALY的增量成本为8817欧元,体育锻炼为14571欧元。在既定的每QALY支付意愿阈值21536欧元(20000英镑)下,与常规治疗相比,ICBT具有成本效益的概率为90%,体育锻炼为76%。

结论

从初级保健的角度来看,与常规治疗相比,用于治疗抑郁症的ICBT和体育锻炼可能都具有成本效益。

利益声明

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd7c/6060490/0dd7740677e7/S2056472418000388_fig1.jpg

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