Zachariae H
Scand J Infect Dis Suppl. 1985;47:44-50.
Herpesviruses which affect man are herpes simplex virus type 1 and type 2, varicella-zoster virus, cytomegalovirus and Epstein-Barr virus. The review deals with the more common clinical manifestations of human herpesvirus infections, which occur ubiquitously in all populations throughout the world. Primary infections most commonly occur in childhood. It is a characteristic feature of herpesvirus that they generally remain in a latent form after clearance of the primary infection. The overall majority of clinical problems are related to activated latent infections, viz. recurrent lesions of herpes simplex, herpes zoster with remaining neuralgia in older patients, and in particular herpesvirus infections and reactivation in immunodeficient individuals. Herpes infection during pregnancy may result in severe generalised infection of the newborn. A possible relationship between herpesvirus and cancer, especially between herpesvirus type 2 and cervical cancer and between Epstein-Barr virus and Burkitt's lymphoma are of major interest today.
感染人类的疱疹病毒有1型和2型单纯疱疹病毒、水痘-带状疱疹病毒、巨细胞病毒和爱泼斯坦-巴尔病毒。本综述探讨人类疱疹病毒感染更常见的临床表现，这些感染在世界各地的所有人群中普遍存在。原发性感染最常见于儿童期。疱疹病毒的一个特征是，在原发性感染清除后，它们通常会以潜伏形式存在。绝大多数临床问题与潜伏感染激活有关，即单纯疱疹的复发性损害、老年患者带状疱疹伴后遗神经痛，尤其是免疫缺陷个体的疱疹病毒感染和再激活。孕期疱疹感染可能导致新生儿严重的全身性感染。疱疹病毒与癌症之间可能存在的关系，尤其是2型疱疹病毒与宫颈癌之间以及爱泼斯坦-巴尔病毒与伯基特淋巴瘤之间的关系，是当今人们主要关注的问题。
