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在一家专注于创伤外科的诊所中评估糖尿病和营养不良对患者术后并发症发生率及生活质量的影响。

Assessment of the Influence of Diabetes mellitus and Malnutrition on the Postoperative Complication Rate and Quality of Life of Patients in a Clinic Focused on Trauma Surgery.

作者信息

Wintermeyer Elke, Ihle Christoph, Ehnert Sabrina, Schreiner Anna J, Stollhof Laura, Stöckle Ulrich, Nussler Andreas, Fritsche Andreas, Pscherer Stefan

机构信息

BG Unfallklinik Tübingen, Eberhard Karls Universität Tübingen.

Abteilung Endokrinologie, Diabetologie, Angiologie, Nephrologie und Klinische Chemie, Eberhard Karls Universität Tübingen.

出版信息

Z Orthop Unfall. 2019 Apr;157(2):173-182. doi: 10.1055/a-0654-5504. Epub 2018 Jul 31.

Abstract

BACKGROUND

The prevalence of diabetes mellitus (DM) or malnutrition in hospitalised patients depends on the clinical domain, but is much higher than in the normal population. In trauma surgery, this increase is frequently associated with more postoperative complications and constantly rising costs. In addition, the quality of life of this target group is decreased, but there are only limited data from departments of traumatology and/or orthopaedics. Therefore, we aim to analyse the factors influencing the postoperative complication rate as well as the quality of life of orthopaedic and trauma patients.

METHODS

Within this prospective trial in the period of 06/2014 to 02/2017, we analysed data of 1643 patients from traumatology - geriatric and septic traumatology - as well as endoprosthetics with regard to the clinical outcome, the complication rate and the quality of life (Short Form Health Survey 36, SF-36) associated with diabetes mellitus (DM) and the nutritional status (Nutritional Risk Screening 2002, NRS).

RESULTS

Within our hospitalised group of trauma patients, the prevalence of diabetes mellitus was 12.4% and the risk for malnutrition (NRS ≥ 3) was 18.3%, which is much higher than in the normal population (DM 7.2%). Patients suffering from diabetes mellitus had significantly more complications than patients without diabetes mellitus. Similar results were found when comparing patients with a risk of malnutrition to the patients without. Furthermore, patients with DM evaluate their subjective quality of life lower than do patients without DM in the most domains of the SF-36, especially in the subjective-physical domains, while patients with NRS ≥ 3 assess their quality of life as being lower than do patients without a risk of malnutrition in all domains of the SF-36 (physical and mental). Additionally, we showed that reduced nutritional status has a greater influence on the decline in quality of life than did diabetes mellitus.

CONCLUSION

Both diabetes mellitus and malnutrition seems to influence the subjective quality of life and the complication rate of hospitalised trauma patients. A nationwide data collection and targeted interventions within the frame of interdisciplinary cooperation are necessary. In this way, the postoperative complication rate as well as associated higher treatment costs could be reduced.

摘要

背景

住院患者中糖尿病(DM)或营养不良的患病率取决于临床领域,但远高于正常人群。在创伤外科中,这种增加常与更多术后并发症及持续上升的费用相关。此外,这一目标群体的生活质量下降,但创伤科和/或骨科部门的数据有限。因此,我们旨在分析影响骨科和创伤患者术后并发症发生率及生活质量的因素。

方法

在这项2014年6月至2017年2月期间的前瞻性试验中,我们分析了来自创伤科(老年创伤科和脓毒症创伤科)以及关节置换术的1643例患者的数据,涉及临床结局、并发症发生率以及与糖尿病(DM)和营养状况(营养风险筛查2002,NRS)相关的生活质量(健康调查简表36,SF - 36)。

结果

在我们的住院创伤患者组中,糖尿病患病率为12.4%,营养不良风险(NRS≥3)为18.3%,远高于正常人群(糖尿病7.2%)。糖尿病患者比无糖尿病患者有更多并发症。将有营养不良风险的患者与无此风险的患者比较时也发现了类似结果。此外,糖尿病患者在SF - 36的大多数领域中对其主观生活质量的评价低于无糖尿病患者,尤其是在主观身体领域,而NRS≥3的患者在SF - 36的所有领域(身体和心理)中对其生活质量的评价低于无营养不良风险的患者。此外,我们表明营养状况下降对生活质量下降的影响比糖尿病更大。

结论

糖尿病和营养不良似乎都影响住院创伤患者的主观生活质量和并发症发生率。有必要在跨学科合作框架内进行全国性数据收集和针对性干预。这样可以降低术后并发症发生率以及相关的更高治疗费用。

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