Nanxishan Hospital of Guangxi Zhuang Autonomous Region, Guangxi Zhuang Autonomous Region Second People's Hospital, Breast surgery, Guilin, Guangxi, China.
Sci Rep. 2018 Jul 31;8(1):11494. doi: 10.1038/s41598-018-29946-x.
Post Mastectomy Pain Syndrome (PMPS) is a common postoperative condition for breast cancer, but has been ignored. The aim of this study was to investigate the prevalence of PMPS and the risk factors in women submitted to surgical treatment for breast cancer. The study included 532 postoperative breast cancer patients in a hospital for five consecutive years period, of whom 473 were considered eligible and included in the study. A total of 420 people completed a questionnaire survey, which revealed that 152 (36.2%) had ever suffered from PMPS and 18 (11.8%) sought treatment. Of the patients with PMPS, 34 (22.4%) had a history of chronic pain. Patients with PMPS were younger than patients without PMPS (50.5 ± 10.4 vs 53.5 ± 11.1). Univariate analysis showed that age, history of chronic pain, tumor staging, number of lymphadenectomy were significantly different between the two groups. Multivariate analysis shows that age and history of chronic pain were independent risk factors. The incidence of PMPS in postoperative breast cancer patients can reach 36.2%, and age as well as previous history of pain are independent risk factors for PMPS. The combination of prevention and treatment may be an effective way to reduce PMPS.
乳腺癌术后乳房疼痛综合征（PMPS）是一种常见的术后病症，但一直被忽视。本研究旨在调查接受乳腺癌手术治疗的女性中 PMPS 的患病率和危险因素。该研究包括连续五年在一家医院接受手术治疗的 532 例乳腺癌术后患者，其中 473 例符合条件并被纳入研究。共有 420 人完成了问卷调查，结果显示 152 人（36.2%）曾患有 PMPS，18 人（11.8%）曾寻求治疗。在患有 PMPS 的患者中，有 34 人（22.4%）有慢性疼痛病史。患有 PMPS 的患者比没有 PMPS 的患者年轻（50.5±10.4 岁 vs 53.5±11.1 岁）。单因素分析显示，两组间年龄、慢性疼痛史、肿瘤分期、淋巴结清扫术数量差异有统计学意义。多因素分析显示，年龄和慢性疼痛史是 PMPS 的独立危险因素。乳腺癌术后患者 PMPS 的发生率可达到 36.2%，年龄和既往疼痛史是 PMPS 的独立危险因素。预防和治疗的结合可能是降低 PMPS 的有效方法。
