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J Obstet Gynaecol India. 2018 Aug;68(4):314-319. doi: 10.1007/s13224-018-1131-7. Epub 2018 May 16.
2
Mini-Laparoscopy for Removal (Partial) of Adnexae at the Time of Hysterectomy.子宫切除时采用迷你腹腔镜(部分)切除附件
J Minim Invasive Gynecol. 2017 Feb;24(2):201-202. doi: 10.1016/j.jmig.2016.11.005. Epub 2016 Nov 14.
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Gynecol Oncol. 2013 Jun;129(3):448-51. doi: 10.1016/j.ygyno.2013.03.023. Epub 2013 Apr 2.
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J Minim Invasive Gynecol. 2017 Jan 1;24(1):145-150. doi: 10.1016/j.jmig.2016.08.833. Epub 2016 Sep 13.
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Risks and benefits of opportunistic salpingectomy during vaginal hysterectomy: a decision analysis.阴道子宫切除术中机会性输卵管切除术的风险与益处:一项决策分析
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Examining indicators of early menopause following opportunistic salpingectomy: a cohort study from British Columbia, Canada.探讨加拿大不列颠哥伦比亚省机会性输卵管切除术(salpingectomy)后早绝经的指标:一项队列研究。
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Extending the safety evidence for opportunistic salpingectomy in prevention of ovarian cancer: a cohort study from British Columbia, Canada.延长机会性输卵管切除术预防卵巢癌的安全性证据:来自加拿大不列颠哥伦比亚省的队列研究。
Am J Obstet Gynecol. 2018 Aug;219(2):172.e1-172.e8. doi: 10.1016/j.ajog.2018.05.019. Epub 2018 May 28.

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2
Hysterectomy with opportunistic salpingectomy versus hysterectomy alone.全子宫切除术加选择性输卵管切除术与单纯全子宫切除术的比较。
Cochrane Database Syst Rev. 2019 Aug 28;8(8):CD012858. doi: 10.1002/14651858.CD012858.pub2.

本文引用的文献

1
The Effect of Salpingectomy on Ovarian Function.输卵管切除术对卵巢功能的影响。
J Minim Invasive Gynecol. 2017 May-Jun;24(4):563-578. doi: 10.1016/j.jmig.2017.02.014. Epub 2017 Feb 20.
2
Opportunistic salpingectomy for ovarian cancer prevention.用于预防卵巢癌的机会性输卵管切除术。
Gynecol Oncol Res Pract. 2015 Sep 17;2:5. doi: 10.1186/s40661-015-0014-1. eCollection 2015.
3
Bilateral salpingectomy can reduce the risk of ovarian cancer in the general population: A meta-analysis.双侧输卵管切除术可降低普通人群患卵巢癌的风险:一项荟萃分析。
Eur J Cancer. 2016 Mar;55:38-46. doi: 10.1016/j.ejca.2015.12.003. Epub 2016 Jan 8.
4
Surgical outcomes and complications of prophylactic salpingectomy at the time of benign hysterectomy in premenopausal women.绝经前女性良性子宫切除术时预防性输卵管切除术的手术结果及并发症
J Minim Invasive Gynecol. 2015 May-Jun;22(4):653-7. doi: 10.1016/j.jmig.2015.02.013. Epub 2015 Feb 24.
5
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.全球癌症发病与死亡:GLOBOCAN 2012 数据源、方法与主要模式。
Int J Cancer. 2015 Mar 1;136(5):E359-86. doi: 10.1002/ijc.29210. Epub 2014 Oct 9.
6
Prophylactic bilateral salpingectomy (PBS) to reduce ovarian cancer risk incorporated in standard premenopausal hysterectomy: complications and re-operation rate.预防性双侧输卵管切除术(PBS)结合标准绝经前子宫切除术降低卵巢癌风险:并发症和再次手术率。
J Cancer Res Clin Oncol. 2014 May;140(5):859-65. doi: 10.1007/s00432-014-1622-6. Epub 2014 Feb 27.
7
Physician opinions regarding elective bilateral salpingectomy with hysterectomy and for sterilization.医生对选择性双侧输卵管切除术联合子宫切除术和绝育的意见。
J Minim Invasive Gynecol. 2013 Jul-Aug;20(4):517-21. doi: 10.1016/j.jmig.2013.02.010.
8
Salpingectomy as standard at hysterectomy? A Danish cohort study, 1977-2010.输卵管切除术作为子宫切除术的标准术式?一项丹麦队列研究,1977-2010 年。
BMJ Open. 2013 Jun 20;3(6):e002845. doi: 10.1136/bmjopen-2013-002845.
9
Laparoscopic supracervical hysterectomy with concomitant bilateral salpingectomy--why not?腹腔镜下子宫颈上切除术联合双侧输卵管切除术——为何不可?
Anticancer Res. 2013 Jun;33(6):2771-4.
10
The role of the fallopian tube in the origin of ovarian cancer.输卵管在卵巢癌起源中的作用。
Am J Obstet Gynecol. 2013 Nov;209(5):409-14. doi: 10.1016/j.ajog.2013.04.019. Epub 2013 Apr 10.

低风险绝经前女性行全腹腔镜子宫切除术时进行双侧输卵管切除的13年经验

Thirteen Years of Experience with Opportunistic Bilateral Salpingectomy During TLH in Low-Risk Premenopausal Women.

作者信息

Paul P G, Mannur Sumina, Shintre Hemant, Paul George, Gulati Gunjan, Mehta Santwan

机构信息

Centre for Advanced Endoscopy and Infertility Treatment, Paul's Hospital, Vattekkattu Road, Kaloor, Kochi, Kerala 682 017 India.

出版信息

J Obstet Gynaecol India. 2018 Aug;68(4):314-319. doi: 10.1007/s13224-018-1131-7. Epub 2018 May 16.

DOI:10.1007/s13224-018-1131-7
PMID:30065548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6046681/
Abstract

BACKGROUND

Opportunistic bilateral salpingectomy (OBS), also called as prophylactic salpingectomy or risk-reducing salpingectomy is the concurrent removal of the fallopian tubes in premenopausal women. Though there are some studies comparing the intraoperative complications and effect of salpingectomy on ovarian reserve, limited data are available on long-term follow-up after OBS.

PURPOSE OF THE STUDY

To evaluate the surgical outcome of routine bilateral salpingectomy during total laparoscopic hysterectomy (TLH) in terms of intraoperative and postoperative complications. We also evaluated the incidence and reoperation rate for adnexal pathology after TLH.

METHODS

A retrospective study of 1470 patients undergoing total laparoscopic hysterectomy (TLH) with opportunistic bilateral salpingectomy (OBS) over 13 years was carried out at Paul's Hospital.

RESULTS

The mean age of the subjects was 43.6 ± 4.2 years, mean body mass index was 27 ± 5.4 kg/m, and median parity was 2 (range 0-7). 43% of women had at least one previous surgery. The most common indication for surgery was fibroid uterus (67%,  = 985). The total complication rate was 4.4% ( = 65). One specimen showed paratubal borderline serous malignancy. The follow-up period ranged from 6 months to 13 years during which 17 (1.1%) women had adnexal pathology, and eight women (1.1%) needed resurgery for it. No ovarian malignancies were reported on follow-up.

CONCLUSIONS

OBS is a simple and short surgical step during TLH without increasing morbidity. OBS eliminates the risk of future diseases of tubal origin, and there might be a possible reduction in incidence and reoperation rate for future ovarian pathologies.

摘要

背景

机会性双侧输卵管切除术(OBS),也称为预防性输卵管切除术或降低风险的输卵管切除术,是指在绝经前女性中同时切除双侧输卵管。尽管有一些研究比较了输卵管切除术的术中并发症以及对卵巢储备功能的影响,但关于OBS术后长期随访的数据有限。

研究目的

从术中及术后并发症方面评估全腹腔镜子宫切除术(TLH)中常规双侧输卵管切除术的手术结果。我们还评估了TLH术后附件病变的发生率及再次手术率。

方法

在保罗医院对1470例在13年期间接受全腹腔镜子宫切除术(TLH)并进行机会性双侧输卵管切除术(OBS)的患者进行了一项回顾性研究。

结果

研究对象的平均年龄为43.6±4.2岁,平均体重指数为27±5.4kg/m²,中位产次为2次(范围0 - 7次)。43%的女性既往至少接受过一次手术。最常见的手术指征是子宫肌瘤(67%,n = 985)。总并发症发生率为4.4%(n = 65)。一份标本显示输卵管旁交界性浆液性恶性肿瘤。随访期为6个月至13年,在此期间17例(1.1%)女性出现附件病变,8例(1.1%)女性因此需要再次手术。随访期间未报告卵巢恶性肿瘤。

结论

OBS是TLH过程中一个简单且耗时短的手术步骤,不会增加发病率。OBS消除了未来输卵管源性疾病的风险,并且可能会降低未来卵巢病变的发生率及再次手术率。