State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiang'an South Road, Xiamen, 361102, China.
Department of Anesthesiology, Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China.
Environ Geochem Health. 2019 Aug;41(4):1847-1860. doi: 10.1007/s10653-018-0159-z. Epub 2018 Jul 31.
Ocean acidification (OA) and crude oil pollution have been highlighted as some of the most pervasive anthropogenic influences on the ocean.In marine teleosts, early life-history stages are particularly vulnerable to disturbance by CO-driven acidification as they lack pH-mediated intracellular regulation. Embryos exposed to trace levels of crude oil constituents dissolved in water exhibit a common syndrome of developmental abnormalities. So far, little is known about the combined effects of OA and crude oil on the early life history of marine fish. Eggs and larvae of the marine medaka (Oryzias melastigma) were treated with CO (1080 μatm atmospheric CO), the water-soluble fraction (WSF) of crude oil (500 μg/L) and a CO (1080 μatm atmospheric CO)/WSF (500 μg/L) mixture within 4 h after oviposition. Isolated and combined OA/WSF had no detectable effect on embryonic duration, egg survival rate and size at hatching. Histopathological anomalies of tissue and lipid metabolic disorder were significant when CO or WSF was given alone at 30 days of age. Combination of CO and WSF enhanced their toxicity compared to their separate administration. Since the early life-history stage of marine fish is thought to be impacted more heavily by increasing CO partial pressure (pCO) levels and crude oil pollution, OA and crude oil pollution have the potential to act as an additional source of natural mortality.
海洋酸化（OA）和原油污染已被强调为对海洋影响最广泛的人为因素之一。在海洋硬骨鱼类中，早期生命史阶段特别容易受到 CO 驱动酸化的干扰，因为它们缺乏 pH 介导的细胞内调节。暴露于溶解在水中的微量原油成分的胚胎表现出一种常见的发育异常综合征。到目前为止，对于 OA 和原油对海洋鱼类早期生活史的综合影响知之甚少。在产卵后 4 小时内，用 CO（1080 μatm 大气 CO）、原油的水溶性部分（WSF）（500 μg/L）和 CO（1080 μatm 大气 CO）/WSF（500 μg/L）混合物处理海洋稻鱼（Oryzias melastigma）的卵和幼虫。单独和联合 OA/WSF 对胚胎持续时间、卵存活率和孵化时的大小没有可检测到的影响。当 CO 或 WSF 在 30 天时单独给药时，组织的组织学异常和脂质代谢紊乱具有显著意义。CO 和 WSF 的组合增强了它们的毒性，与它们的单独给药相比。由于海洋鱼类的早期生命史阶段被认为受到 CO 分压（pCO）水平升高和原油污染的影响更大，因此 OA 和原油污染有可能成为自然死亡率的另一个来源。
