Yang Hsien-Yi, Su Bor-Cherng, Hwang Ming-Jay, Lee Yi-Pang
Department of Dentistry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Department of Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Tzu Chi Med J. 2018 Jul-Sep;30(3):185-187. doi: 10.4103/tcmj.tcmj_57_18.
Fibrous dysplasia (FD) is a rare bony disorder in which normal bone is replaced by abnormal fibro-osseous tissue. It often involves the long bones, craniofacial bones, ribs, and pelvis. Approximately 30% of monostotic FD (MFD) lesions are found in the cranial or facial bones. In general, FD is found in teenagers, and it usually becomes static after adulthood. FD involves the maxilla almost two times more often than the mandible. It frequently appears in the posterior region of the jaw bone and is usually unilateral. Here, we present an unusual case of symptomatic MFD affecting the anterior region of the mandible in a 43-year-old female with the clinical, radiographical, and histopathological features. The clinical examination showed both the labial and lingual bone expansion in the anterior mandible. The radiographic examination revealed a lesion with both radiopaque and radiolucent features showing a "ground-glass" appearance. The diagnosis was obtained after confirmatory intrabony biopsy with the histopathological examination, and it was diagnosed with benign FD. The patient preferred regular follow-up of MFD after discussion. During the regular follow-up, MFD lesion showed no obvious signs of progression or malignancy features.
骨纤维异常增殖症（FD）是一种罕见的骨疾病，其中正常骨被异常的纤维骨组织所取代。它常累及长骨、颅面骨、肋骨和骨盆。约30%的单骨型FD（MFD）病变见于颅骨或面骨。一般来说，FD多见于青少年，成年后通常会静止。FD累及上颌骨的频率几乎是下颌骨的两倍。它常出现在颌骨后部，且通常为单侧。在此，我们报告一例43岁女性的罕见病例，其有症状的MFD累及下颌骨前部，具有临床、影像学和组织病理学特征。临床检查显示下颌骨前部唇侧和舌侧骨均有膨隆。影像学检查显示一个具有不透光和透光特征的病变，呈“磨玻璃”样外观。经骨内活检及组织病理学检查确诊，诊断为良性FD。经讨论后，患者选择对MFD进行定期随访。在定期随访期间，MFD病变未显示出明显的进展迹象或恶性特征。
