[Chemical Constituents from Roots of Gentiana straminea of Tibetan Medicine].

OBJECTIVE

To investigate the chemical constituent from the roots of Gentiana straminea.

METHODS

The constituents were separated by microporous resin,silica gel,Sephadex LH-20 and preparative column chromatography and their structures were elucidated by NMR and MS spectral methods.

RESULTS

Twelve chemical constituents were isolated from the roots of Gentiana straminea and their structures were identified as daucosterol( 1),β-sitosterol( 2),ursolic acid( 3),sweroside( 4),swertiamarin( 5),gentiopicroside( 6),6’-O-acetyl-gentiopicroside( 7),6’-O-β-D-glucopyranosyl-sweroside( 8),protocatech uic aldehyde( 9),protocatechuic acid( 10),methyl gallate( 11) and dibutyl phthalate( 12).

CONCLUSION

The compounds 8,9,10,11 and 12 are obtained from this plant for the first time.