Abedini Atefeh, Kiani Arda, Taghavi Kimia, Khalili Ali, Fard Alireza Jahangiri, Fadaizadeh Lida, Salimi Alireza, Parsa Tahereh, Aarabi Akram, Farzanegan Behrooz, Tootkaboni Mahsa Pourabdollah
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tracheal Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Turk Thorac J. 2018 Jul;19(3):127-131. doi: 10.5152/TurkThoracJ.2018.17025. Epub 2018 Jul 1.
High-frequency jet ventilation (HFJV) is a convenient method for providing ventilation during fiberoptic bronchoscopy. We describe an incipient approach of high-frequency jet ventilation via the working channel of a flexible bronchoscope for nonintubated patients who suffer from hypoxemia during bronchoscopy. The aim of this study was to test the efficacy of this incipient approach and determine the possible complications related to it.
Sixteen patients who had oxygen saturation below 70% that did not resolve with nasal oxygen for 20 s during interventional bronchoscopy were included in the study. High-frequency jet ventilation was administrated via the working channel of a bronchoscope for 3 min. Arterial blood gas circumscriptions were compared before and after jet ventilation.
Oxygen saturation increased to >90% in all patients 30 s after jet ventilation. Mean arterial oxygen saturation pressure increased from 54.84 to 111.98 mmHg with jet ventilation (p=0.0001). Arterial carbon dioxide tension decreased after jet ventilation. The body mass index had no consequential effect on arterial carbon dioxide pressure after jet ventilation in our patients (p=0.1). Complications such as pneumothorax and working channel damage were not observed.
High-frequency jet ventilation via the working channel of the bronchoscope is a novel method that can provide optimal ventilation with minimal complications to nonintubated patients suffering from hypoxemia during bronchoscopy. This method also reduces the duration of bronchoscopy procedures.
高频喷射通气（HFJV）是在纤维支气管镜检查期间提供通气的一种便捷方法。我们描述了一种通过柔性支气管镜工作通道对在支气管镜检查期间出现低氧血症的非插管患者进行高频喷射通气的初步方法。本研究的目的是测试这种初步方法的有效性，并确定与之相关的可能并发症。
纳入16例在介入性支气管镜检查期间经鼻吸氧20秒后血氧饱和度仍低于70%的患者。通过支气管镜的工作通道进行高频喷射通气3分钟。比较喷射通气前后的动脉血气指标。
喷射通气30秒后，所有患者的血氧饱和度均升至>90%。喷射通气时，平均动脉血氧饱和压从54.84 mmHg升至111.98 mmHg（p = 0.0001）。喷射通气后动脉二氧化碳分压降低。在我们的患者中，体重指数对喷射通气后的动脉二氧化碳压力没有显著影响（p = 0.1）。未观察到气胸和工作通道损伤等并发症。
通过支气管镜工作通道进行高频喷射通气是一种新方法，可为支气管镜检查期间出现低氧血症的非插管患者提供最佳通气，且并发症最少。该方法还缩短了支气管镜检查的时间。
