Tehrani Khadijeh Haji Naghi
Department Neurology, Islamic Azad University, Tehran Medical Sciences Branch, Tehran, Iran.
Open Access Maced J Med Sci. 2018 Jul 14;6(7):1239-1243. doi: 10.3889/oamjms.2018.263. eCollection 2018 Jul 20.
The use of the MRI method has opened up a new perspective on pathogenesis, diagnosis and treatment of brain lesions.
Therefore, this study aimed to evaluate the prevalence of brain subclinical lesions in MRI images of migraine patients.
This cross-sectional study was conducted on 300 patients with a migraine referred to Baqiyatallah and Amir Al-Momenin Hospitals from 2005 to 2006. We measured the relationship between the results of MRI and the type of brain subclinical lesion by indices such as age, gender, type of a migraine, the number of migraine attacks, blood pressure and heart diseases, cholesterol, diabetes and thyroid diseases. Finally, data were analysed by IBM SPSS statistics software version 23. The significance level in this study was considered as P > 0.05.
From among 300 patients, 87.7% were women in the age range of 13-72 years. Moreover, the results indicated that with increasing age, blood pressure and some migraine attacks, the frequency of abnormal MRI also is increased significantly as well as the ratio of a migraine with aura was significantly higher than a migraine without aura in individuals with abnormal MRI. Also, the ratio of white matter lesions (WML) is higher in a classical migraine (a Migraine with aura). Statistical analyses did not reveal any significant relationship between MRI results on age, diabetes, cholesterol, heart and thyroid diseases.
The prevalence of abnormal MRI in older people and those with high blood pressure and migraine with aura is higher, and the ratio of subclinical lesions in the population of a migraine with aura is more common than a migraine without aura.
磁共振成像（MRI）方法的应用为脑损伤的发病机制、诊断和治疗开辟了新的视角。
因此，本研究旨在评估偏头痛患者MRI图像中脑亚临床损伤的患病率。
这项横断面研究于2005年至2006年对300例转诊至巴基耶塔拉和阿米尔·穆民医院的偏头痛患者进行。我们通过年龄、性别、偏头痛类型、偏头痛发作次数、血压和心脏病、胆固醇、糖尿病和甲状腺疾病等指标来衡量MRI结果与脑亚临床损伤类型之间的关系。最后，数据采用IBM SPSS统计软件23版进行分析。本研究中的显著性水平设定为P>0.05。
300例患者中，87.7%为女性，年龄在13至72岁之间。此外，结果表明，随着年龄、血压和偏头痛发作次数的增加，MRI异常的频率也显著增加，而且在MRI异常的个体中，有先兆偏头痛的比例显著高于无先兆偏头痛。另外，典型偏头痛（有先兆偏头痛）中白质病变（WML）的比例更高。统计分析未发现MRI结果与年龄、糖尿病、胆固醇、心脏和甲状腺疾病之间存在任何显著关系。
老年人、高血压患者以及有先兆偏头痛患者的MRI异常患病率较高，而且有先兆偏头痛人群中亚临床损伤的比例比无先兆偏头痛人群更为常见。
