Abdalla Khalid, Alawneh Khaled Z, Al-Bdour Mohammad, Abu-Salih Abdel Qader
Department of Diagnostic Radiology and Nuclear Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Head Face Med. 2025 Feb 15;21(1):6. doi: 10.1186/s13005-024-00478-2.
This study aims to investigate the association between patients with migraine headaches and brain magnetic resonance imaging (MRI) findings.
Migraine is a frequently encountered primary headache disorder with a disproportionate female predominance. Diagnosis is usually based on the patient's clinical history with neuroimaging reserved for severe or atypical presentations to exclude other pathologies. Migraine patients often experience a profound impact on their quality of life.
A retrospective study was conducted at King Abdullah University Hospital, Jordan, involving patients with a clinical diagnosis of migraine who had undergone MRI brain imaging between January 2021 to March 2023. Descriptive data were documented, with two independent neuro-radiologists interpreting MRI findings.
Our study included 670 migraine patients (510 females; mean age, 40.3 years). White matter hyperintensity lesions were found in 309 patients (46.1%), significantly affecting older age groups with a mean age of 46.8 years (p > 0.001). Additionally, gender played a role, with a higher prevalence of these lesions in female migraine patients, accounting for 79.6% (p = 0.05). Multiple logistic regression analysis proved age to be an independent risk factor for the presence of white matter hyperintensity lesions (OR: 1.0688, 95% CI: 1.0546-1.0831, p > 0.001).
White matter hyperintensity lesions were seen in the MRI imaging of a subset of migraine patients. Patients with these lesions tend to be older and of female gender. However, the clinical significance of these findings remains unclear.
本研究旨在调查偏头痛患者与脑磁共振成像（MRI）结果之间的关联。
偏头痛是一种常见的原发性头痛疾病，女性患病率过高。诊断通常基于患者的临床病史，对于严重或非典型表现则进行神经影像学检查以排除其他病变。偏头痛患者的生活质量常受到严重影响。
在约旦阿卜杜拉国王大学医院进行了一项回顾性研究，纳入2021年1月至2023年3月期间接受过脑部MRI成像且临床诊断为偏头痛的患者。记录描述性数据，由两名独立的神经放射科医生解读MRI结果。
我们的研究包括670例偏头痛患者（510例女性；平均年龄40.3岁）。309例患者（46.1%）发现有白质高信号病变，这些病变在平均年龄为46.8岁的老年人群中影响显著（p>0.001）。此外，性别也有影响，女性偏头痛患者中这些病变的患病率更高，占79.6%（p=0.05）。多元逻辑回归分析证明年龄是白质高信号病变存在的独立危险因素（OR：1.0688，95%CI：1.0546-1.0831，p>0.001）。
在一部分偏头痛患者的MRI成像中发现了白质高信号病变。有这些病变的患者往往年龄较大且为女性。然而，这些发现的临床意义仍不明确。
