持续的尖峰活动是工作记忆的基础。
Persistent Spiking Activity Underlies Working Memory.
机构信息
Department of Neurobiology & Anatomy, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157,
Kokoro Research Center, Kyoto University, Yoshida Sakyo-ku, Kyoto, 606-8501, Japan.
出版信息
J Neurosci. 2018 Aug 8;38(32):7020-7028. doi: 10.1523/JNEUROSCI.2486-17.2018.
Abstract
Persistent activity generated in the PFC during the delay period of working memory tasks represents information about stimuli held in memory and determines working memory performance. Alternative models of working memory, depending on the rhythmicity of discharges or exclusively on short-term synaptic plasticity, are inconsistent with the neurophysiological data.Working Memory: Delay Activity, Yes! Persistent Activity? Maybe Not, by Mikael Lundqvist, Pawel Herman, and Earl K. Miller.
摘要
工作记忆任务延迟期前额叶皮层中持续的活动代表了记忆中保持的刺激信息，并决定了工作记忆的表现。其他工作记忆模型，无论是依赖于放电的节律性还是仅依赖于短期突触可塑性，都与神经生理学数据不一致。工作记忆：延迟活动，是的！持续活动？也许不是，作者：Mikael Lundqvist、Pawel Herman 和 Earl K. Miller。
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