Kanazawa Takuya, Takezawa Takahiro, Iwamoto Junichi, Adachi Yoshikazu
School of Agriculture, Ibaraki University, 3-21-1 Ami, Ibaraki 300-0393, Japan.
Department of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan.
J Vet Med Sci. 2018 Sep 13;80(9):1416-1419. doi: 10.1292/jvms.18-0220. Epub 2018 Aug 7.
We succeeded in the simultaneous isolation of Brachyspira (B.) aalborgi and B. pilosicoli from a patient with ulcerative colitis. B. pilosicoli grew quickly and formed colonies within 7 days, while the growth of B. aalborgi was very slow and took over 21 days. Simultaneous isolation of B. pilosicoli and B. aalborgi from a common specimen is generally recognized to be difficult, mainly due to differences in their growth requirements and the growth rates. However, we succeeded in isolating both species from a patient with ulcerative colitis and this is first evidence. The present results suggest that ulcerative colitis may be caused by simultaneous infection with B. pilosicoli and B. aalborgi.
我们成功地从一名溃疡性结肠炎患者体内同时分离出了阿尔堡短螺旋体（Brachyspira (B.) aalborgi）和柔毛短螺旋体（B. pilosicoli）。柔毛短螺旋体生长迅速，7天内即可形成菌落，而阿尔堡短螺旋体的生长非常缓慢，需要21天以上。一般认为，从同一标本中同时分离出柔毛短螺旋体和阿尔堡短螺旋体很困难，主要是由于它们的生长需求和生长速度不同。然而，我们成功地从一名溃疡性结肠炎患者体内分离出了这两种菌株，这是首个证据。目前的结果表明，溃疡性结肠炎可能是由柔毛短螺旋体和阿尔堡短螺旋体同时感染引起的。
