Zhenjiang Center for Disease Control and Prevention, Jiangsu, China.
Zhenjiang First People's Hospital, Jiangsu, China.
Int J Infect Dis. 2018 Sep;74:38-40. doi: 10.1016/j.ijid.2018.07.001. Epub 2018 Jul 6.
Human immunodeficiency virus (HIV)/AIDS is a major public health problem worldwide. Here we report the case of a patient with positive HIV-1 serology and negative result of The COBAS AmpliPrep/COBAS Taqman HIV-1 Test version 2.0 (CAP/CTM v2.0) assay (Roche Diagnostics) for HIV-1 RNA quantification in the absence of antiretroviral therapy (ARV). Considering the HIV contact history and repeating serological confirmatory test is essential before considering a low or even undetectable HIV-1 viral load to be a false-negative result.
人类免疫缺陷病毒（HIV）/艾滋病是全球主要的公共卫生问题。在这里，我们报告了一例患者 HIV-1 血清学阳性和罗氏诊断公司的 COBAS AmpliPrep/COBAS Taqman HIV-1 Test version 2.0（CAP/CTM v2.0）检测 HIV-1 RNA 定量的结果为阴性，该患者未接受抗逆转录病毒治疗（ARV）。考虑到 HIV 接触史，在将 HIV-1 病毒载量低甚至无法检出视为假阴性结果之前，重复血清学确认试验至关重要。
