Morley David, Dummett Sarah, Kelly Laura, Jenkinson Crispin
Nuffield Department of Population Health, University of Oxford, Oxford, UK,
Patient Relat Outcome Meas. 2018 Jul 25;9:239-243. doi: 10.2147/PROM.S160263. eCollection 2018.
The recently validated Oxford Participation and Activities Questionnaire (Ox-PAQ) is a 23-item patient-reported outcome measure, theoretically grounded in the World Health Organization International Classification of Functioning, Disability and Health. The measure is specifically designed to assess participation and activity in people experiencing a range of health conditions. Initial validation of the Ox-PAQ identified three domains: Routine Activities (14 items), Emotional Well-Being (5 items), and Social Engagement (4 items). The purpose of the analysis reported here was to assess whether the Routine Activities domain of Ox-PAQ could be validated for use as a stand-alone measure without compromising its psychometric integrity.
Three hundred and seventy-three patients with a diagnosis of either chronic obstructive pulmonary disease, multiple sclerosis, or Parkinson's disease were administered the Ox-PAQ in an online survey. The 14 items of the Routine Activities domain of the Ox-PAQ were subject to factor analytic techniques and assessed for reliability and validity.
Three hundred and forty-one patients fully completed the survey, a completion rate of 91.4%. The 14 items loaded onto one single factor with an eigenvalue of 9.29 explaining 66.35% of variance. Reliability was confirmed through corrected item-total correlations ranging from 0.880 to 0.594 and a Cronbach's alpha value of 0.96. Validity was demonstrated through significant differences in scores between the three disease groups assessed.
Results indicate that the Ox-PAQ Routine Activities domain can be legitimately adopted as a stand-alone measure, the Oxford Routine Activities Measure, where researchers wish to focus primarily on the activity component of the Ox-PAQ. It should, however, be emphasized that where a full assessment of all areas of activity and participation highlighted as important during the development of the Ox-PAQ is required, all three domains of the full measure should be administered.
最近经过验证的牛津参与和活动问卷（Ox-PAQ）是一项包含23个条目的患者报告结局指标，理论基础为世界卫生组织的《国际功能、残疾和健康分类》。该指标专门设计用于评估患有一系列健康状况的人群的参与和活动情况。Ox-PAQ的初步验证确定了三个领域：日常活动（14个条目）、情绪幸福感（5个条目）和社会参与（4个条目）。此处报告的分析目的是评估Ox-PAQ的日常活动领域能否在不损害其心理测量完整性的情况下被验证为一项独立指标。
在一项在线调查中，对373名诊断为慢性阻塞性肺疾病、多发性硬化症或帕金森病的患者进行了Ox-PAQ调查。对Ox-PAQ日常活动领域的14个条目进行因子分析技术处理，并评估其信度和效度。
341名患者完全完成了调查，完成率为91.4%。14个条目加载到一个单一因子上，特征值为9.29，解释了66.35%的方差。通过校正的条目-总分相关性（范围为0.880至0.594）和克朗巴赫α值0.96确认了信度。通过评估的三个疾病组之间得分的显著差异证明了效度。
结果表明，当研究人员希望主要关注Ox-PAQ的活动部分时，Ox-PAQ日常活动领域可以合法地作为一项独立指标采用，即牛津日常活动指标。然而，应该强调的是，在需要全面评估Ox-PAQ开发过程中突出的所有活动和参与领域时，应使用完整指标的所有三个领域。
