Morley David, Dummett Sarah, Kelly Laura, Dawson Jill, Jenkinson Crispin
Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Old Road Campus, Oxford, OX3 7LF, UK.
Health Qual Life Outcomes. 2015 Jan 23;13:5. doi: 10.1186/s12955-014-0193-1.
The 39-item Parkinson's Disease Questionnaire (PDQ-39) is the most thoroughly validated and extensively used self-report measure for the assessment of health-related quality of life in people with Parkinson's (PwP). Given the extent of its use and increasing emphasis on electronic data capture, an e-based version of the PDQ-39, the ePDQ, has recently been developed. The aim of this short report is to present some key reliability and validity data that confirm the psychometric quality of the ePDQ.
Participants were emailed a unique link to an online survey incorporating the ePDQ and demographic questions. A total of 118 PwP fully completed the survey. Floor and ceiling effects were calculated to ensure responses were not biased to extreme values. Consequently, score reliability was assessed by item-total correlations with a range from 0.34 to 0.90. Cronbach's alpha was calculated at between 0.64 and 0.95 for the eight domains of the ePDQ. Construct validity was assessed by comparing domain scores in relation to disease duration and gender, with hypothesised differences being largely confirmed. Construct validity was further assessed following a higher order factor analysis which confirmed the appropriateness of calculating a summary index score. Subsequently, significant, but moderate correlations were calculated between the ePDQ summary index score and disease duration and age at diagnosis.
Results indicate that the ePDQ largely mirrors the properties of its parent instrument, the PDQ-39, in terms of reliability and validity. Potential users can therefore incorporate the ePDQ into computer-based data capture systems with confidence.
39项帕金森病问卷（PDQ - 39）是评估帕金森病患者健康相关生活质量方面经过最全面验证且使用最广泛的自我报告测量工具。鉴于其使用范围以及对电子数据采集的日益重视，最近开发了基于电子版本的PDQ - 39，即ePDQ。本简短报告的目的是呈现一些关键的信度和效度数据，以证实ePDQ的心理测量质量。
通过电子邮件向参与者发送了一个包含ePDQ和人口统计学问题的在线调查的唯一链接。共有118名帕金森病患者完全完成了调查。计算了地板效应和天花板效应，以确保回答不会偏向极端值。因此，通过项目 - 总分相关性评估得分信度，范围为0.34至0.90。ePDQ的八个领域的Cronbach's alpha系数计算结果在0.64至0.95之间。通过比较与疾病持续时间和性别的领域得分来评估结构效度，假设的差异在很大程度上得到了证实。在进行高阶因子分析后进一步评估结构效度，该分析证实了计算汇总指数得分的适当性。随后，计算出ePDQ汇总指数得分与疾病持续时间和诊断时年龄之间存在显著但中等程度的相关性。
结果表明，ePDQ在信度和效度方面很大程度上反映了其母体工具PDQ - 39的特性。因此，潜在用户可以放心地将ePDQ纳入基于计算机的数据采集系统。
