Khoo Leng Wei, Audrey Kow Siew, Lee Ming Tatt, Tan Chin Ping, Shaari Khozirah, Tham Chau Ling, Abas Faridah
Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Department Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
Evid Based Complement Alternat Med. 2018 Jul 4;2018:9276260. doi: 10.1155/2018/9276260. eCollection 2018.
(Burm.f.) Lindau (Acanthaceae), commonly known as Sabah snake grass, is a vegetable and a well-known herb that is considered an alternative medicine for insect bites, skin rashes, herpes infection, inflammation, and cancer and for health benefits. Current review aims to provide a well-tabulated repository of the phytochemical screening, identification and quantification, and the pharmacological information of according to the experimental design and the plant preparation methods which make it outstanding compared to existing reviews. This review has documented valuable data obtained from all accessible library databases and electronic searches. For the first time we analyzed the presence of flavonoids, triterpenoids, steroids, phytosterols, and glycosides in based on the results from phytochemical screening which are then further confirmed by conventional phytochemical isolation methods and advanced spectroscopic techniques. Phytochemical quantification further illustrated that is a good source of phenolics and flavonoids. Pharmacological studies on revealed that its polar extract could be a promising anti-inflammation, antiviral, anticancer, immune and neuromodulating, and plasmid DNA protective agent; that its semipolar extract could be a promising antiviral, anticancer, and wound healing agent; and that its nonpolar extract could be an excellent anticancer agent.
（缅甸）林道（爵床科），俗称沙巴蛇草，是一种蔬菜，也是一种著名的草药，被认为是治疗昆虫叮咬、皮疹、疱疹感染、炎症和癌症的替代药物，且对健康有益。当前的综述旨在根据实验设计和植物制备方法，提供一份详细列表的资料库，内容包括植物化学筛选、鉴定和定量以及其药理学信息，这使其与现有综述相比显得尤为突出。本综述记录了从所有可获取的图书馆数据库和电子搜索中获得的有价值的数据。我们首次根据植物化学筛选结果分析了其黄酮类、三萜类、甾体类、植物甾醇类和糖苷类的存在情况，随后通过传统植物化学分离方法和先进光谱技术进一步证实。植物化学定量进一步表明，它是酚类和黄酮类的良好来源。对其进行的药理学研究表明，其极性提取物可能是一种有前景的抗炎、抗病毒、抗癌、免疫和神经调节以及质粒DNA保护剂；其半极性提取物可能是一种有前景的抗病毒、抗癌和伤口愈合剂；其非极性提取物可能是一种出色的抗癌剂。
