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(Burm. f.)Lindau 的抗病毒和免疫调节活性。

Antiviral and Immunomodulatory Activities of (Burm. f.) Lindau.

机构信息

Department of Biotechnology, School of Health Technology, Ming Chuan University, Taoyuan 33348, Taiwan.

Division of Plastic and Reconstructive Surgery, Department of Surgery, China Medical University Hospital, Taichung 40402, Taiwan.

出版信息

Int J Mol Sci. 2023 Jun 28;24(13):10789. doi: 10.3390/ijms241310789.

Abstract

(Burm. f.) Lindau has been used as a traditional herbal medicine for treating snake bites, scalds, burns, and viral and bacterial infections. It has been attracting an increasing amount of attention because of its biological activities, including its antidiabetic, antioxidant, antibacterial, anticancer, anti-inflammatory, antiviral, and immunoregulatory activities. Here, we conducted a panoramic survey of the literature regarding the immunoregulatory, anti-inflammatory, and antiviral activities of . We discovered that extracts have virucidal activities against herpes simplex virus types 1 and 2, varicella-zoster virus, cyprinid herpesvirus 3, porcine reproductive and respiratory syndrome virus, mosquito-borne chikungunya virus, and potentially SARS-CoV-2; such activities likely result from interfering with the entry, penetration, infection, and replication of viruses. We also reviewed the phytochemicals in extracts that exhibit anti-inflammatory and immunoregulatory activities. This updated review of the antiviral, anti-inflammatory, and immunoregulatory activities of may guide future agricultural practices and reveal clinical applications of .

摘要

(缅甸)林达已被用作传统草药,用于治疗蛇咬伤、烫伤、烧伤以及病毒和细菌感染。由于其具有生物活性,包括抗糖尿病、抗氧化、抗菌、抗癌、抗炎、抗病毒和免疫调节活性,因此引起了越来越多的关注。在这里,我们对有关 的免疫调节、抗炎和抗病毒活性的文献进行了全面调查。我们发现, 提取物对单纯疱疹病毒 1 型和 2 型、水痘带状疱疹病毒、鲤鱼疱疹病毒 3、猪繁殖与呼吸综合征病毒、蚊媒基孔肯雅病毒和可能的 SARS-CoV-2 具有抗病毒活性;这种活性可能是由于 干扰病毒的进入、穿透、感染和复制。我们还回顾了 提取物中具有抗炎和免疫调节活性的植物化学物质。对 的抗病毒、抗炎和免疫调节活性的更新综述可能指导未来的农业实践,并揭示 的临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1091/10342181/3c3e0370ae60/ijms-24-10789-g001.jpg

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