REMbrandt 研究，一项包含大量脑癌患者基因组数据的大型研究。
The REMBRANDT study, a large collection of genomic data from brain cancer patients.
机构信息
Innovation Center for Biomedical Informatics (ICBI), Georgetown University Medical Center, Washington DC 20007, USA.
National Cancer Institute, Rockville, MD, USA.
出版信息
Sci Data. 2018 Aug 14;5:180158. doi: 10.1038/sdata.2018.158.
The Rembrandt brain cancer dataset includes 671 patients collected from 14 contributing institutions from 2004-2006. It is accessible for conducting clinical translational research using the open access Georgetown Database of Cancer (G-DOC) platform. In addition, the raw and processed genomics and transcriptomics data have also been made available via the public NCBI GEO repository as a super series GSE108476. Such combined datasets would provide researchers with a unique opportunity to conduct integrative analysis of gene expression and copy number changes in patients alongside clinical outcomes (overall survival) using this large brain cancer study.
伦勃朗脑癌数据集包含 671 名患者，这些患者是从 2004 年至 2006 年期间的 14 个提供机构中收集的。它可以通过开放获取的乔治城癌症数据库（G-DOC）平台进行临床转化研究。此外，原始和处理后的基因组学和转录组学数据也通过公共 NCBI GEO 存储库以超级系列 GSE108476 的形式提供。这些综合数据集将为研究人员提供一个独特的机会，使用这项大型脑癌研究，对患者的基因表达和拷贝数变化以及临床结果（总生存期）进行综合分析。
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