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利用云芝属真菌胞外合成生物相容性硫化镉量子点。

Extracellular biosynthesis of biocompatible cadmium sulfide quantum dots using Trametes versicolor.

机构信息

Shandong Provincial Key Lab. of Microbial Engineering, Qi Lu University of Technology, Shandong Academy of Sciences, Jinan 250353, PR China.

Shandong Provincial Key Lab. of Microbial Engineering, Qi Lu University of Technology, Shandong Academy of Sciences, Jinan 250353, PR China.

出版信息

J Biotechnol. 2018 Oct 20;284:52-56. doi: 10.1016/j.jbiotec.2018.08.004. Epub 2018 Aug 11.

Abstract

Quantum dots are important fluorescent semiconductor nano-crystals with distinguished electrical and optical properties and have gained great interest in many fields. The chemical and physical synthetic methods are usually not favorable for biological application due to high energy-consumption procedure and residual toxic chemicals. The development of novel "green" routes to prepare bio-compatible cadmium sulfide quantum dots constitutes a promising substituted approach. We used the white rot fungus Trametes versicolor for the biosynthesis of cadmium sulfide quantum dots taking account of the adsorption property of this fungus. Multiple physical characterizations involving scanning electron microscope (SEM), ultraviolet-visible (UV-vis) and photoluminescence (PL) spectroscopy, fourier transform infrared spectroscopy (FTIR), thermo-gravimetric (TG), transmission electron microscopy (TEM) and X-ray diffraction (XRD) confirmed surface, optical and thermal characteristics, crystalline nature, size and shape distributions of the nanoparticles. This study provided a suitable and efficient approach to synthesize stable biocompatible cadmium sulfide quantum dots using the fungus Trametes versicolor with great potentials in the biological and biomedical researches.

摘要

量子点是具有显著电、光学性质的重要荧光半导体纳米晶体,在许多领域引起了极大的兴趣。由于高能耗工艺和残留有毒化学物质,化学和物理合成方法通常不利于生物应用。开发新型“绿色”方法来制备生物相容性的硫化镉量子点是一种很有前途的替代方法。考虑到这种真菌的吸附特性,我们使用白腐真菌糙皮侧耳来合成硫化镉量子点。多种物理特性分析,包括扫描电子显微镜(SEM)、紫外-可见(UV-vis)和光致发光(PL)光谱、傅里叶变换红外光谱(FTIR)、热重(TG)、透射电子显微镜(TEM)和 X 射线衍射(XRD),证实了纳米颗粒的表面、光学和热特性、晶体性质、尺寸和形状分布。这项研究提供了一种合适且高效的方法,使用白腐真菌糙皮侧耳来合成稳定的生物相容性硫化镉量子点,在生物和生物医学研究中具有很大的潜力。

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