• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在开放性楔形高位胫骨截骨术中将人工骨用作间隙填充物时,人工骨上制造孔洞并去除空气对早期骨形成的优势。

Advantages of creation of holes and removal of air in artificial bone for early bone formation when used artificial bone as a gap filler in open wedge high tibial osteotomy.

作者信息

Tohma Yasuaki, Takeuchi Ryohei, Tanaka Yasuhito

机构信息

Department of Orthopaedic Surgery, Nara City Hospital, 1-50-1, Higashi-Kidera-cho, Nara, Nara, Japan.

Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Nara, Japan.

出版信息

Eur J Orthop Surg Traumatol. 2019 Jan;29(1):131-137. doi: 10.1007/s00590-018-2286-8. Epub 2018 Aug 17.

DOI:10.1007/s00590-018-2286-8
PMID:30120535
Abstract

Recently, many facilities perform open wedge high tibial osteotomy (OWHTO) using artificial bone as a gap filler. However, there are many cases in which artificial bone is used without a clear purpose. We recommend a surgical technique to promote early synostosis between artificial bone and recipient bone due to mechanical support especially in the early stage after OWHTO. At our hospital, beta-tricalcium phosphate (β-TCP) with 60% porosity is used in OWHTO. Initially, a wedge-shaped block-type β-TCP, as large as possible, was inserted into the gap. However, from the standpoint of initial mechanical support, we changed the artificial bone size and created intentional holes. Furthermore, we removed air bubbles from β-TCP. We evaluated the synostosis on the basis of clinical results and diagnostic imaging. As a result of creating holes and removing air from the artificial bone, a trend toward faster synostosis was noted, especially at the early stage. No adverse events such as tibial plateau fracture, lateral cortical fracture, plate and screw failure and correction loss due to reducing the size of the artificial bone occurred, but placement of the artificial bone in contact with cortical bone and surface contact installation with the recipient bone tissue was important. When using artificial bone in OWHTO, holes formation and removal of air from the artificial bone are recommended for faster synostosis between artificial bone and recipient bone in the early stage after surgery. Artificial bone should be used, with attention to its positioning and shape, for efficient mechanical support.

摘要

最近,许多医疗机构在进行开放性楔形高位胫骨截骨术(OWHTO)时使用人工骨作为间隙填充物。然而,在很多情况下,人工骨的使用并无明确目的。我们推荐一种手术技术,尤其是在OWHTO术后早期,通过机械支撑促进人工骨与受体骨之间的早期骨融合。在我们医院,孔隙率为60%的β-磷酸三钙(β-TCP)被用于OWHTO。最初,将尽可能大的楔形块状β-TCP插入间隙。然而,从初始机械支撑的角度出发,我们改变了人工骨的尺寸并制造了有意的孔洞。此外,我们从β-TCP中去除了气泡。我们根据临床结果和诊断成像评估骨融合情况。由于在人工骨上制造孔洞并去除空气,观察到骨融合有加快的趋势,尤其是在早期。未发生诸如胫骨平台骨折、外侧皮质骨折、钢板和螺钉失效以及因减小人工骨尺寸导致的矫正丢失等不良事件,但人工骨与皮质骨接触放置以及与受体骨组织表面接触安装很重要。在OWHTO中使用人工骨时,建议在人工骨上制造孔洞并去除空气,以在术后早期实现人工骨与受体骨之间更快的骨融合。应注意人工骨的定位和形状,以便有效地发挥机械支撑作用。

相似文献

1
Advantages of creation of holes and removal of air in artificial bone for early bone formation when used artificial bone as a gap filler in open wedge high tibial osteotomy.在开放性楔形高位胫骨截骨术中将人工骨用作间隙填充物时,人工骨上制造孔洞并去除空气对早期骨形成的优势。
Eur J Orthop Surg Traumatol. 2019 Jan;29(1):131-137. doi: 10.1007/s00590-018-2286-8. Epub 2018 Aug 17.
2
Bone formation and resorption in patients after implantation of beta-tricalcium phosphate blocks with 60% and 75% porosity in opening-wedge high tibial osteotomy.在开放性楔形高位胫骨截骨术中植入孔隙率为60%和75%的β-磷酸三钙骨块后患者的骨形成与吸收情况
J Biomed Mater Res B Appl Biomater. 2008 Aug;86(2):453-9. doi: 10.1002/jbm.b.31041.
3
Tricalcium phosphate granules or rigid wedge preforms in open wedge high tibial osteotomy: a radiological study with a new evaluation system.磷酸三钙颗粒或开放楔形高位胫骨截骨术中的刚性楔形预成型件:一项采用新评估系统的放射学研究
Knee. 2004 Dec;11(6):451-6. doi: 10.1016/j.knee.2004.08.004.
4
Lateral hinge fracture delays healing of the osteotomy gap in opening wedge high tibial osteotomy with a beta-tricalcium phosphate block.外侧铰链骨折会延迟使用β-磷酸三钙骨块进行的开放楔形高位胫骨截骨术中截骨间隙的愈合。
Knee. 2020 Jan;27(1):192-197. doi: 10.1016/j.knee.2019.10.027. Epub 2019 Dec 26.
5
The role of bone void fillers in medial opening wedge high tibial osteotomy: a systematic review.骨缺损填充材料在胫骨内侧高位开口楔形截骨术中的作用:一项系统评价
Knee Surg Sports Traumatol Arthrosc. 2016 Nov;24(11):3584-3598. doi: 10.1007/s00167-016-4297-5. Epub 2016 Aug 24.
6
Faster bone union progression and less sclerosis at the osteotomy margin after medial opening-wedge high tibial osteotomy using highly porous β-tricalcium phosphate granules versus allogeneic bone chips: A matched case-control study.内侧开口楔形胫骨高位截骨术中使用高孔隙率β-磷酸三钙颗粒与同种异体骨屑相比,更快的骨愈合进展和更少的截骨边缘硬化:一项配对病例对照研究。
Knee. 2021 Mar;29:33-41. doi: 10.1016/j.knee.2021.01.017. Epub 2021 Feb 4.
7
Gap healing after medial open-wedge high tibial osteotomy using injectable beta-tricalcium phosphate.使用可注射β-磷酸三钙进行内侧开放楔形高位胫骨截骨术后的骨间隙愈合
J Orthop Surg (Hong Kong). 2017 Sep-Dec;25(3):2309499017727942. doi: 10.1177/2309499017727942.
8
Combined use of beta-tricalcium phosphate with different porosities can accelerate bone remodelling in open-wedge high tibial osteotomy.不同孔隙率的β-磷酸三钙联合使用可加速开放性楔形高位胫骨截骨术中的骨重塑。
Asia Pac J Sports Med Arthrosc Rehabil Technol. 2022 Jul 5;29:30-34. doi: 10.1016/j.asmart.2022.05.004. eCollection 2022 Jul.
9
In vitro stability of open wedge high tibial osteotomy with synthetic bone graft.使用人工骨移植的开放楔形高位胫骨截骨术的体外稳定性
Knee. 2010 Jun;17(3):217-20. doi: 10.1016/j.knee.2009.09.002. Epub 2009 Oct 4.
10
Resorbability of rigid beta-tricalcium phosphate wedges in open-wedge high tibial osteotomy: a retrospective radiological study.开放性楔形高位胫骨截骨术中刚性β-磷酸三钙楔块的可吸收性:一项回顾性影像学研究
Knee. 2008 Jun;15(3):201-5. doi: 10.1016/j.knee.2008.02.005. Epub 2008 Apr 14.

本文引用的文献

1
Bone Defect Regeneration by a Combination of a β-Tricalcium Phosphate Scaffold and Bone Marrow Stromal Cells in a Non-Human Primate Model.在非人类灵长类动物模型中,β-磷酸三钙支架与骨髓基质细胞联合用于骨缺损再生
Open Biomed Eng J. 2016 Mar 18;10:2-11. doi: 10.2174/1874120701610010002. eCollection 2016.
2
Effect of Wedge Insertion Angle on Posterior Tibial Slope in Medial Opening Wedge High Tibial Osteotomy.楔形插入角度对内侧开口楔形胫骨高位截骨术胫骨后倾角的影响。
Orthop J Sports Med. 2016 Feb 25;4(2):2325967116630748. doi: 10.1177/2325967116630748. eCollection 2016 Feb.
3
Beta-tricalcium phosphate shows superior absorption rate and osteoconductivity compared to hydroxyapatite in open-wedge high tibial osteotomy.
β-磷酸三钙在开放式胫骨高位截骨术中的吸收率和骨传导性优于羟磷灰石。
Knee Surg Sports Traumatol Arthrosc. 2014 Nov;22(11):2763-70. doi: 10.1007/s00167-013-2681-y. Epub 2013 Sep 18.
4
Opening wedge high tibial osteotomy performed without filling the defect but with locking plate fixation (TomoFix™) and early weight-bearing: prospective evaluation of bone union, precision and maintenance of correction in 51 cases.未填充骨缺损行楔形胫骨高位截骨术(TomoFixTM)并采用锁定钢板固定,术后早期负重:51 例患者骨愈合、截骨精度和矫形维持的前瞻性评估
Orthop Traumatol Surg Res. 2011 Nov;97(7):705-11. doi: 10.1016/j.otsr.2011.06.011. Epub 2011 Oct 15.
5
Efficient cell-seeding into scaffolds improves bone formation.高效地将细胞接种到支架中可以促进骨形成。
J Dent Res. 2010 Aug;89(8):854-9. doi: 10.1177/0022034510370022. Epub 2010 Jun 8.
6
The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering.平均孔径对用于骨组织工程的胶原糖胺聚糖支架中细胞黏附、增殖和迁移的影响。
Biomaterials. 2010 Jan;31(3):461-6. doi: 10.1016/j.biomaterials.2009.09.063. Epub 2009 Oct 9.
7
In vitro stability of open wedge high tibial osteotomy with synthetic bone graft.使用人工骨移植的开放楔形高位胫骨截骨术的体外稳定性
Knee. 2010 Jun;17(3):217-20. doi: 10.1016/j.knee.2009.09.002. Epub 2009 Oct 4.
8
Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges.应用 Ceraver 可吸收β-磷酸三钙楔形骨片行胫骨撑开楔形截骨术治疗严重内翻畸形。
Int Orthop. 2010 Feb;34(2):191-9. doi: 10.1007/s00264-009-0875-1. Epub 2009 Oct 1.
9
Measurement of tibial slope angle after medial opening wedge high tibial osteotomy: case series.内侧开放楔形高位胫骨截骨术后胫骨坡度角的测量:病例系列
Sao Paulo Med J. 2009 Jan;127(1):34-9. doi: 10.1590/s1516-31802009000100008.
10
Bone regeneration with autologous plasma, bone marrow stromal cells, and porous beta-tricalcium phosphate in nonhuman primates.非人类灵长类动物中自体血浆、骨髓基质细胞和多孔β-磷酸三钙用于骨再生的研究
Tissue Eng Part A. 2009 Jul;15(7):1489-99. doi: 10.1089/ten.tea.2008.0317.