含钼和钨的甲酸盐脱氢酶和甲酰甲硫氨酸脱氢酶：结构、机制和辅因子插入。
Molybdenum- and tungsten-containing formate dehydrogenases and formylmethanofuran dehydrogenases: Structure, mechanism, and cofactor insertion.
机构信息
Department of Biochemistry, University of California, Riverside.
出版信息
Protein Sci. 2019 Jan;28(1):111-122. doi: 10.1002/pro.3498. Epub 2018 Oct 31.
Abstract
An overview is provided of the molybdenum- and tungsten-containing enzymes that catalyze the interconversion of formate and CO , focusing on common structural and mechanistic themes, as well as a consideration of the manner in which the mature Mo- or W-containing cofactor is inserted into apoprotein.
摘要
提供了一个概述，介绍了催化甲酸盐和 CO 相互转化的含钼和钨的酶，重点介绍了常见的结构和机制主题，以及考虑了成熟的 Mo 或 W 含辅因子插入到脱辅蛋白中的方式。
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本文引用的文献
1
Efficient reduction of CO by the molybdenum-containing formate dehydrogenase from ().来自（）的含钼甲酸脱氢酶对CO的高效还原作用。
J Biol Chem. 2017 Oct 13;292(41):16872-16879. doi: 10.1074/jbc.M117.785576. Epub 2017 Aug 7.
2
Oxidation-State-Dependent Binding Properties of the Active Site in a Mo-Containing Formate Dehydrogenase.氧化态依赖的钼含甲酸脱氢酶活性位点的结合特性。
J Am Chem Soc. 2017 Jul 26;139(29):9927-9936. doi: 10.1021/jacs.7b03958. Epub 2017 Jul 17.
3
The methanogenic CO2 reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters.产甲烷二氧化碳还原固定酶具有双功能，包含 46 个 [4Fe-4S]簇。
Science. 2016 Oct 7;354(6308):114-117. doi: 10.1126/science.aaf9284.
4
The physiology and habitat of the last universal common ancestor.最后普遍共同祖先的生理学和栖息地。
Nat Microbiol. 2016 Jul 25;1(9):16116. doi: 10.1038/nmicrobiol.2016.116.
5
Reduction of Carbon Dioxide by a Molybdenum-Containing Formate Dehydrogenase: A Kinetic and Mechanistic Study.含钼甲酸盐脱氢酶还原二氧化碳：动力学和机理研究。
J Am Chem Soc. 2016 Jul 20;138(28):8834-46. doi: 10.1021/jacs.6b03941. Epub 2016 Jul 7.
6
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Biochemistry. 2016 Apr 26;55(16):2381-9. doi: 10.1021/acs.biochem.6b00002. Epub 2016 Apr 18.
7
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J Biol Chem. 2016 Jan 15;291(3):1162-74. doi: 10.1074/jbc.M115.688457. Epub 2015 Nov 9.
8
Sulfido and cysteine ligation changes at the molybdenum cofactor during substrate conversion by formate dehydrogenase (FDH) from Rhodobacter capsulatus.在荚膜红细菌甲酸脱氢酶（FDH）进行底物转化过程中，钼辅因子处的硫代和半胱氨酸连接发生变化。
Inorg Chem. 2015 Apr 6;54(7):3260-71. doi: 10.1021/ic502880y. Epub 2015 Mar 24.
9
Sulphur shuttling across a chaperone during molybdenum cofactor maturation.硫原子在钼辅因子成熟过程中穿越伴侣蛋白。
Nat Commun. 2015 Feb 4;6:6148. doi: 10.1038/ncomms7148.
10
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