Koch Jennifer K Lange, Miguel Helga, Smiley-Oyen Ann L
Department of Kinesiology, Iowa State University, 534 Wallace Road, Ames, IA, 50011, USA.
University of Minho, 4710-057, Braga, Portugal.
Exp Brain Res. 2018 Nov;236(11):3053-3064. doi: 10.1007/s00221-018-5358-4. Epub 2018 Aug 18.
We used near-infrared spectroscopy to examine dorsolateral prefrontal cortex (DLPFC) activation over time in 10 children with or at-risk-for developmental coordination disorder (DCD) and 11 typically developing children (ages 8-12) during tasks involving executive processing. The groups performed with similar accuracy on the Stroop and Wisconsin card sort (WCST), but their underlying neural activation differed. Typically developing children modulated DLPFC activity over time and showed rightward lateralization during Stroop but no lateralization during WCST. The DCD group exhibited high and sustained activation across hemispheres and tasks, which we suggest is a compensatory effort to maintain response accuracy.
我们使用近红外光谱技术，在涉及执行加工的任务过程中，对10名患有发育性协调障碍（DCD）或有患该疾病风险的儿童以及11名发育正常的儿童（8至12岁），随时间推移检测其背外侧前额叶皮层（DLPFC）的激活情况。两组在斯特鲁普任务和威斯康星卡片分类测验（WCST）中的表现准确性相似，但他们潜在的神经激活情况有所不同。发育正常的儿童随时间调节DLPFC活动，在斯特鲁普任务中表现出右侧化，但在WCST中没有出现侧化。DCD组在两个半球和各项任务中均表现出较高且持续的激活，我们认为这是为维持反应准确性而做出的一种代偿努力。
